The quality of vaccines is still often tested by using laboratory animals. That has to change, according to researchers from Leiden University and the vaccinological institute Intravacc. Together they went searching for a test method that makes animal testing unnecessary. The first promising results…

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countries. Bioneedles, which are biodegradable mini-implants,…

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Leiden University is awarding an honorary doctorate to virologist Marc van Ranst. Van Ranst has been one of the main advisers of the Belgian government during the Covid pandemic. German Arabist Beatrice Gründler will also receive an honorary doctorate for her work in the field of Oriental Manuscript…

The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…

Epithelial cells play a crucial role in the lungs. PhD student Ying Wang researched the effects of cigarette smoke and viruses such as COVID-19 on these epithelial cells. ‘We hope to reduce the risk of pandemics in the future.’

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

If you'll soon be getting a COVID-19 vaccine, you might just get the Johnson & Johnson (Janssen) one. This vaccine was developed for the most part in Leiden – and this is no coincidence. Watch the animation below about the development of one of the vaccines in the fight against COVID-19.

Scientists at the LUMC are working hard on potential virus inhibitors, antiviral screening and a treatment for COVID-19. SteunLeiden.nl has started a crowdfunding campaign for this research, under the hashtag #wakeuptocorona. Professor of Virology Eric Snijder explains why this is desperately needed…

Knowing how to resolve global problems is one thing, but how do you make sure that it actually happens? That’s the real challenge, because there are powerful movements everywhere that want to reconstruct the walls of nation states. In an attempt to resolve this issue, Leiden researchers are experimenting…

Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.

By detecting the tiny forces between a micrometer sized magnet and the spins of hydrogen nuclei, we can do MRI with a volume resolution that is approximately 12 orders of magnitude better than a conventional MRI.  

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

Isotopes on exoplanets, a more efficient memory for data centres or new molecules that work against the Zika virus and HIV. Which PhD candidate has written the most impressive dissertation of 2023? The jury of the C.J. Kok Jury Award faces the challenging task of deciding that. Meet the nominees of…

Interest groups play an important role in democratic society.

Fake news about ‘patient zero’ and hyperbolic headlines warning about the ‘yellow peril.’ Leiden researchers have spotted fake news galore about coronavirus as well as racial stereotypes about the Chinese. How harmful is this?

What do I do if Mum or Dad gets the virus? Could the slide at the playground have coronavirus on it? Can children die of the virus too? On 15 April, the National Science Agenda organised an hour-long session on Facebook to give children the chance to ask their questions about coronavirus. Leiden psychologist…

We are confronted on a daily basis with news about the Corona virus and its consequences. We read alarming headlines like 'Dutch becoming increasingly anxious about Corona virus' or 'Huge fears and stress about Corona crisis'.

Important note: upon careful consideration, we have decided to resume our Dutch language courses.

A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.

Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…

The research group of Eric Snijder, Professor of Molecular Virology (LUMC), has been conducting research on coronaviruses for decades. Then in March this year their work accelerated at an unprecedented rate. The first new results are now available: insight into how the virus replicates.

Jelle van Buuren, Assistant Professor at Leiden University, appeared in Dutch newspapers the Algemeen Dagblad and Het Parool to discuss conspiracy thinking and the pandemic.

The end of October will be all about the United Nations (UN). The festivities for the 75th anniversary have been scaled down due to the corona virus. 'A shame', says Prof.dr. Alanna O'Malley, but at the same time she sees that corona crisis also offers opportunities for the UN.

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

An overview of awards and prizes granted to our staff and students in 2019, as well as special appointments and royal distinctions.

Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…

How are Dutch universities working together in times of corona, and which solutions are they offering? On 15 May VSNU chairman Pieter Duisenberg presented the e-zine ‘Universities in times of corona’ (LINK) to Ingrid Van Engelshoven, Minister of Education, Culture and Science. The e-zine contains a…

Prehistoric people may well have had an emotional bond with domesticated dogs much earlier than we thought. Leiden PhD candidate and vet Luc Janssens discovered that a dog found at the start of the last century in a grave dating back 14,000 years had been sick for a long time and had been cared for.…

At the end of the year we always compile a list of our most interesting, most popular articles from that year. In the crazy year that was 2020 one topic was at the forefront of everyone’s minds: coronavirus. Fortunately, there was also room for other stories.

Why have some European countries responded faster to the coronavirus outbreak than others? While in some countries the lockdown had already been declared when relatively few cases were known, others did not take action until thousands of people were already infected and hundreds were already dead. What…

September 26 is the European Day of Languages. There are 24 official languages in Europe but some 200 languages in total are spoken on our continent. What good are all these different languages? And should we all learn Azerbaijani or Swedish? We asked Lisa Cheng, Professor of General Linguistics.

On April 8th 2020, Ivan Romashchenko successfully defended his doctoral thesis on 'Related party transactions and corporate groups: When Eastern Europe meets the West'.

The Netherlands in September 2021 could be characterised as a low-trust society. Trust in the government has declined significantly in the past one-and-a-half years: from almost 70 percent in April 2020 to less than 30 percent in September 2021. There has also been a slight decrease in trust between…

At the end of March, the first coronavirus infections were detected in southern Africa, which resulted in country after country rapidly closing their borders. Tycho van der Hoog witnessed this process at first hand during his PhD research in Namibia. He analyzes the state of the corona crisis from his…

Leiden Asia Centre researcher Anoma van der Veere argues that the Japanese government has failed to respond properly to Covid-19. There were difficulties with implementing government measures aimed at limiting the spread of the virus – in some cases those measures were not even taken seriously. How…

Zijn corona-complotten waanzin? Jelle van Buuren, universitair docent bij het Institute of Security and Global Affairs van de Universiteit Leiden, discussieert in de online talkshow De Groene Live #25 vanuit Pakhuis de Zwijger over dit thema.

There is an ongoing struggle between the Minister of Public Health, Hugo de Jonge, and the Dutch Municipal Health Services (GGDs). De Jonge wants the GGDs to speed up testing, conduct more tests, and allow priority testing but the GGDs are pulling on the brakes. The waiting lists for a corona test have…

Dr. Kirsten Leiss and Prof. Peter Klinkhamer received 900.000 euro’s from “Stichting Toegepaste Wetenschappen (STW)” and the company “Rijk Zwaan” to develop plants that are resistant to thrips, a major agricultural pest all over the world.

Almost all PhD defences at Leiden University have been postponed due to the corona virus, but statistician Sanne Willems is going through with hers. In a different form than usual that is. Hardly any audience, the committee dialing in from a distance and the celebration to be held at a later moment.…

Fourteen bachelor’s and master’s students are representing Leiden University in this year’s International Genetically Engineered Machine competition (iGEM). Their plan: to create a kit that can be used to quickly identify infectious diseases in case of an outbreak.

The 18.8 million euro NWO Zwaartekracht grant for quantum software which Amsterdam, Delft and Leiden landed collectively, means for Leiden University among others the appointment of two new permanent scientific staff members, who will each form their own research group, divided among Computer Science,…

LUMC research has shown that women who previously had a miscarriage due to COVID-19 are not at increased risk of having another miscarriage or a stillbirth. Nor are preventive drugs needed during the pregnancy.

Unfortunately, Covid-19 won’t be the last infectious disease to sweep across the world. To nip such diseases in the bud, a team of Leiden students is developing a test kit that will be able to detect infectious diseases at an early stage. With this idea, they won the Grand Prize of the international…

The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…

The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.

Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…