1,252 search results for “mathematische biology” in the Public website
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Maarten LubbersScience
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Comparative biology of common and grey seals along the Dutch coast
What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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Kees MustersScience
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Louie KrolScience
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Silva Nova – Restoring soil biology and soil functions to gain multiple benefits in new forests
We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…
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Chengyi LiuScience
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Bregje BrinkmannScience
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Pieter BaasScience
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Edi Gittenberger
Science
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August MartinFaculty of Humanities
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context-based educational reform practical for implementatiion in Dutch biology education
For a successful implementation of an educational reform, teachers need to regard the proposal as being practical. I used a modular, success-oriented approach to make a context-based reform practical for implemtentation in Duthc biology education. educational reform, modular, teachers, biology, success-oriented,…
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Major European subsidy for Leiden evolutionary biology
Paul Brakefield, Professor of Evolutionary Biology at the Institute of Biology in Leiden (IBL) has been awarded an ERC Advanced Grant for his research. He will receive 2.5 million euro to develop his research programme over a period of five years.
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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Geert de SnooScience
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Vincent Merckx
Science
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Fien DemuynckScience
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Lina Bayona MaldonadoScience
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Daniel Zumel GeteScience
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Anagnostis TheodoropoulosScience
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Peter van WelzenScience
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Caitlin BlackScience
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Niels Raes
Science
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Han de WindeScience
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Sam BoerlijstScience
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Neeltje BlankensteinFaculteit der Sociale Wetenschappen
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New IBL-professor in Ultrastructural Biology: Ariane Briegel
Ariane Briegel has been appointed Professor in the fìeld of Ultrastructural Biology within the Faculty of Science at the Institute of Biology from the 1st of December 2015. Her expertise is in using electron cryotomography to study how microbes sense and respond to their environment.
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Hans de IonghScience
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Top rating for Biology at Leiden University
Biology is one of the four top educational programs at Leiden University according to the national “Guide to Universities” (Keuzegids Universiteiten).
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Leiden biology appreciated with large NWO grants
A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.
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Teacher knowledge and lesson design
The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…
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IBL symposium “Integrative Biology towards Healthy Communities”
On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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New IBL-professor in "Computational Biology": Vera van Noort
Vera van Noort has been appointed Professor in the field of Computational Biology within the Faculty of Science at the Institute of Biology from the 1st of February 2017. Van Noort’s expertise is in bioinformatics and her research focuses on the computational analysis of large-scale biological data…
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Record number of first-year students for Leiden Biology
150 new Biology students have arrived in Leiden. This is more than ever and we seem to settle among the big three Universities for Biology in the Netherlands.
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Ten million euros for unlocking novel technologies in structural biology
The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…
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Double success at the EMBL Chemical Biology Conference
Thomas Bakkum en Tom van der Wel, two PhD candidates from the Leiden Institute of Chemistry, have both won poster prizes at the EMBL Chemical Biology Conference 2018 in Heidelberg.
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Luka NarishaScience
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Marjolein CrooijmansScience
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Emily StrangeScience
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Lan DupuisScience
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Inaugural lecture: Big pictures of small microbes
Bacteria are everywhere. They are the most abundant organisms on earth and impact all aspects of our lives. They determine our health and shape our environment. Ariane Briegel, professor of Ultrastructural Biology, freezes bacteria super fast to gain a true-to-nature image of the internal and external…
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Delegation of Holland Rijnland visits the Institute of Biology
On Thursday the 24th of November, Tseard Hoekstra and Jeroen Ververs (members of the delegation Holland Rijnland), Geert de Snoo (Dean Faculty of Science), Martina Vijver (CML), Herman Spaink (Scientific Director IBL) and Klaas Vrieling (IBL) explored possibilities for collaborations between companies…