389 search results for “differentiation” in the Public website
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Promoting reading skills through electronic books for grade 1 students
What is the effect of practicing with electronic books on reading skills for grade 1 students?
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Early signs for good mental health during adolescence: Emotional Intelligence matters
In a longitudinal study, Eichengreen and colleagues explored how the certain aspects of emotional intelligence impact the development of adolescents’ mental health, thus identifying potential warning signs and targets for intervention programs. Despite a higher risk for mental health issues and lesser…
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Cell adhesion signaling: dynamics, migration, and metastasis
Cell adhesion signaling
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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Bas ter Braak
Science
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Neurobiological and Environmental Determinants of Parenting and Child Development
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- Planning and Innovation
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Data based decision making processes in secondary education
How can teachers be motivated by their students’ data in making stepwise changes to their teaching practices?
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Waves and Patterns in Discrete Media: Bridging the Gaps
What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body
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Inclusive education - Making the change
Didactics
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Inclusive education (UTQ module)
Didactics
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Regulation of nanoparticle biodistribution by scavenger endothelial cells (SECs)
A very large part of intravenously administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered by macrophages (Kupffer cells). To achieve effective cell-specific targeting of drugs and non-viral gene delivery vectors, improved mechanistic…
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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Why Minor Powers Risk Wars with Major Powers: A Comparative Study of the Post-Cold War Era
Through a range of case studies spanning the post-Cold War period in Iraq, Moldova and Serbia, this book studies asymmetric conflicts where warring sides exhibit vast power differentials.
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Deformations of nodal surfaces
Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk
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Derrida's Politics of Friendship
25 years after the publication of Derrida’s Politics of Friendship (Politiques de l’amitié, 1994), this edited collection gathers 23 critical chapters that revisit this underappreciated text. Engaging closely with Derrida’s text, the contributors analyse, extend and critique the work. They reconsider…
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Language documentation Ecuador
Collaborative linguistic research on indigenous languages of Ecuador: description, documentation & materials
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Translational Symmetry Breaking in Holographic Strange Metals
In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality.
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Figuring Things Out Together: On the Relationship Between Design and Collective Practice
Anja Groten investigates matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D)*.
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Programme structure
The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.
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[sbb] Launching Next-Generation Products in a Competitive Market
When to launch a next-generation product in a competitive market and how much capacity should be allocated to it
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Managing Diversity: Supervising Functions in Managing Colonial Workplaces
Managing Diversity: Supervising Functions in Managing Colonial Workplaces
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United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Crime and gender before the courts of the Netherlands, 1600-1800
The central aim is to systematically study differences in gendered crime patterns in the records of different types of courts in various Dutch cities in the early modern period.
- Science Diplomacy
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Polar auxin transport: translating environmental signals into plant developmental responses
1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…
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Citizenship in a Digital Age
This Research project is funded by the 7th European Community Framework Programme, with additional funds from NWO Aspasia grant, and in collaboration with University of California, Berkeley.
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The Palaeoproteomic Identification of Pleistocene Hominin Skeletal Remains:
Towards a Biological Understanding of the Middle to Upper Palaeolithic Transition
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Synthesis
Abrupt Climate Change and Cultural Transformation
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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XXY versus autism: evidence from neuroimaging
Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI
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A Framework to Navigate Eco-Labels in the Textile and Clothing Industry
This paper provides an initial answer to the question regarding eco-labels: ‘How can we make the development of eco-labels more structured and transparent?’
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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Figuring Things Out Together. On the Relationship Between Design and Collective Practice.
This dissertation explores matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D).
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From respected hermits to ordinary citizens: The conversion of the Baduy, ethnicity, and politics of religion in Indonesia (1977 - 2019)
Mr. Ade Jaya Suryani defended his thesis on 28 January 2021
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Print referencing during e-storybook reading on a SMART board for kindergartners to promote early literacy skills
This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…
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An Ontology for Physical Necessity
The central inquiry of this thesis revolves around how ontology can adequately accommodate the existence of necessary physical relations. Initially, the thesis demonstrates the imperative acknowledgment of necessary physical relations by showcasing the failure of Neo-Humean theories.
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Interpersonal effects of emotions in negotiations
How do different emotional expressions influence the behavior of other people in negotiations?
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Working on Labor. Essays in Honor of Jan Lucassen | Studies in Global Social History, Volume: 9
This collection of seventeen essays takes its inspiration from the scholarly achievements of the Dutch historian Jan Lucassen. They reflect a central theme in his research: the history of labor.
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A Featural Typology of Bantu Agreement
This book explores the fascinating microvariation in Bantu languages and proposes a new syntactic analysis of subject and object agreement crosslinguistically. This book is open access!
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The shell evolution of the Hydrocenidae of Malaysian Borneo
The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.
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The parabolic Anderson model and long-range percolation
Promotor: Prof.dr. F. den Hollander
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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Arqueología en la Linea Noroeste de La Española
Paisaje, cerámicas e interacciones