Luuk van Middelaar and Vestert Borger, both affiliated with the Europa Institute of Leiden University, are conducting a research project that is financed by the Statesman Thorbecke Fund Programme of the Royal Netherlands Academy of Arts and Sciences (KNAW). The aim of the fund is to promote knowledge…

A comprehensive analysis of Nietzsche's conception of conflict and the way in which relations of struggle condition the organisation of complex systems (with a specific focus on the human psyche and the body politic).

Research at the BPOC/SSNMR group is comprised of the following research themes:

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Emphasizing on the key role of polysemy in forming the lexicon is the main goal to be achieved in this dissertation paper. The paper suggests a qualitative evaluation of polysemy in comparing it with other relations that form the lexicon. The research confirms that the polysemic links must not be modeled…

Just published: Nederlands internationaal privaatrecht Special issue: Private international law and finance

Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

This dissertation provides a novel perspective on the interaction between quantifier scope and ellipsis. It presents a detailed investigation of the scopal interaction between English negative indefinites, modals, and quantified phrases in ellipsis. One of the crucial observations is that a negative…

The Department of Business Studies focuses on research questions at the intersection of law and behaviour in the context of organizations and enterprises. The department brings together specialists in entrepreneurship, organizational psychology, marketing, strategy, economics, and finance.

Play and Media is one of the six research themes of the LUCAS Modern and Contemporary cluster.

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…

The linguistic project constitutes the connection between the two other subprojects. It consists of two parts.

Promotor: Prof.dr. S. Haring

Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

This PhD research aims to trace the impact of the Arab conquest, both immediate and long-term, on the material and social organization of Central Asia from 651 to 821 through an “urban change” perspective in four cities: Merv, Paikent, Balkh and Samarkand.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.

‘It became very clear that Brazilian legislative policy was frail, obsolete and unreliable,’ says Felipe de Paula. He defended his dissertation on the limits and possibilities of legislative policy in Brazil on Tuesday 27 March 2018.

This dissertation investigates whether and how gradability is manifested in the nominal domain, as well as the implications this could have for theories of the representation of gradability.

The global agri-food system plays a critical role in food security and environmental issues.

From 1550 onwards, a great interest in the natural world developed across Europe. This interest was not only stimulated by a growing knowledge of local flora and fauna, but also by the import of numerous exotic animal and plant species. Think, for instance, of researches and collectors like Gessner…

The Brazilian economy has long been defined by its enormous potential. Over the past 30 years, some of this has at last been realised. Latin America’s largest economy has rapidly risen in global importance while poverty at home has declined. Yet, despite periods of progress, Brazil remains prone to…

Terrorism has been one of the most important threats to peace, security and stability in many parts of the world. But what does this mean? What is the nature of this threat? What can be done about it and how can we at least limit the impact of terrorism?

This dissertation presents an in-depth study of the clause-typing system in Ecuadorian Siona.

Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.

Using object assemblages to reconstruct activities, modes of deposition and abandonment at the Late Bronze Age dunnu of Tell Sabi Abyad, Syria.

How do humanitarian organisations adapt cyber incidents to their specific priorities and needs, and how can they adapt strategies of other organisations?

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

This pilot project will initiate research on how heritage has been and can be mobilized to address climate change governance in Himalayan Asia. Climate adaptation strategies frequently include the sourcing of heritage, encompassing landscapes, built environments 4 and cultural practices. However, effective…

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

On May 30th, Yang Yang succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Yang on this great result.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Everyone can study at Leiden University, at all stages of life: as undergraduate, master or doctoral students in Leiden or The Hague, or short courses with a choice of interesting and diverse subjects. In fact, by sitting in front of a computer at home, now you also take part in free online programs…

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

In Microbial Sciences, we perform multidisciplinary research to understand the structure and function of microbes at all levels of biological organization, from small molecules and cellular structures at atomic resolution to multicellular communities.

Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.

On 20 februari 2019, Chris van Oostrum defended his thesis 'Regres bij concernfinanciering'. The doctoral research was supervised by Prof. mr. S.M. Bartman.

Loneliness and social isolation have become a significant problem in contemporary Japan. The financial burden associated with an ageing population has severely constrained the ability of local authorities to address the problem. As a result, policymakers have sought cost‐effective methods of tackling…

Honorata Mazepus and Jaroslaw Kantorowicz are assistant professors at the Institute of Security and Global Affairs. Mazepus and Kantorowicz are one of the authors of this article in Nature on the role of national identity on public health support during global pandemics.

TruLife applies lessons from the study of long-term urban traditions, exemplified by pre-Columbian Maya tropical cities, to present-day sustainable urban design.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

November 2020 saw the publication of the book ‘Financial Collateral; Law and Practice’. This book was published by Oxford University Press, and edited and authored by Professor Matthias Haentjens. Other authors who contributed to the book are Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

In this dissertation, electrophysiological (EEG) and behavioural measures are used to investigate how allophonic tonal variants and sub-phonemic features are processed during Mandarin and Dutch speech production, visual processing of written words and reading aloud.

Mei-Wen Chen defended her thesis on 29 June 2016