2,476 search results for “niet studies” in the Public website
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Antibiotic Discovery: From mechanistic studies to target ID
The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.
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Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
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Study of utilization of combined hormonal contraceptives in Europe
Combined hormonal contraceptives (CHC) are associated with an increased risk of venous thromboembolism (VTE). In 2013, a review was published by the European Medicines Agency (EMA). In this review, the authors concluded that the risk of VTE varies by the type of progesterone in the CHC. Subsequently,…
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Voices in stone: Studies in Luwian historical phonology
On the 12th of November, Xander Vertegaal successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Xander on this achievement!
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Language diversity in the psycholinguistic study of sentence form variation
On the 12th of December, Eleanor Dutton successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Eleanor on this achievement.
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Chair of UN Studies in Peace and Justice
From 1 August 2018, Alanna O'Malley was appointed as Chair of United Nations Studies in Peace and Justice, focusing on the ‘lesser-known actors’ of the UN: women, the youth, the agents of informal diplomatic networks within the UN and actors from the Global South. This Special Chair has been created…
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The Lazy Mindreader: a new perspective on “mindreading” from the study of language and narrative
How is social cognition shaped by our knowledge of language and stories?
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The galaxy–dark matter connection: a KiDS study
In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.
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Formalizations après la lettre. Studies in Medieval Logic and Semantics
This thesis attempts to establish a dialogue between the modern and the medieval traditions in logic, by means of ‘translations’ of the medieval logical theories into the modern framework of symbolic logic, i.e. formalizations.
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Prestigious Japanese Fukuoka Prize for Leonard Blussé
Leonard Blussé, emeritus Professor in the History of European and Asian relations, will receive the prestigious Japanese Academic Fukuoka Prize. Blussé receives the prize for creating a new academic field: 'The Maritime History of early modern East/Southeast Asia'. He will receive the Prize in September…
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NMR structural studies of protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Scientists of the Faculty of Governance and Global Affairs about the Terrorist Attacks in Europe
An overview of the media appearances of scientists working with the Faculty of Governance and Global Affairs about terrorist attacks in Europe, their consequences, and more.
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Efficient and flexible platform to isolate and study bacteriophages
We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Computational and Experimental Studies of Reactive Intermediates in Glycosylation Reactions
PhD defence
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Hoven in Holland, 900-1300
In welke mate hebben domaniale structuren de machtsvorming en nederzettingsontwikkeling in en van het gewest Holland bepaald?
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Medieval and Early Modern Studies (c. 600-1800)
This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.
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Case study Käte van Tricht (1909-1996)
The Organ Art of the first female German concert organist and Bremen Cathedral organist and
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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The spiritual Tolkien milieu : a study of fiction‐based religion
Markus Davidsen defended his thesis on 16 October 2014
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Publications
ELS@Leiden research encompasses a wide range of empirical-legal projects carried out within Leiden Law School from the perspective of multiple disciplines and methods. Here you can find the publications of our (former) lab members since the start of the Sector Plan.
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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Voortdurende angst voor het volk
Met de val van Balkenende IV laait de discussie over het functioneren van politieke partijen binnen ons democratisch bestel weer op. Opgeblazen ego’s, overambitieuze politici en partijpolitieke machtspelletjes zouden echte democratie in de weg staan. Maar die discussie is niet nieuw.
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Moleculair mysterie in de ruimte
Tussen de sterren is niet alleen leegte. Er zweven ook stoffen als methanol en koolstofdioxide. Chemische theorieën kunnen nog niet verklaren hoe die zijn ontstaan onder omstandigheden die dat juist onmogelijk zouden moeten maken. Fedor Goumans gaat met een Veni-beurs proberen die vraag te beantwoor…
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Geslaagde studentenconferentie 'empirisch-juridisch onderzoek en het privaatrecht'
Waarom is empirisch-juridisch onderzoek van belang voor de rechtspraktijk en het wetenschappelijke onderzoek? Op die vraag kregen masterstudenten van de afstudeerrichtingen civiel recht, ondernemingsrecht en financieel recht antwoord tijdens het congres over empirisch-juridisch onderzoek en het privaatrecht…
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Gebruiker proof of concept toegang Digitaal Magazijn KB
Voor deze use case zoeken wij een gebruiker die voor onderzoeksdoeleinden interesse heeft in de auteursrechtelijk beschermde collectie van de KB en ons kan helpen met het opstellen door wensen, noden en ervaringen te delen.
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Wetenschappers ontdekken hoe darmbacterie resistent wordt
Een minuscuul cirkelvormig stukje DNA zorgt ervoor dat de darmbacterie Clostridioides difficile resistent raakt tegen een veelgebruikt antibioticum. Dat ontdekten wetenschappers van het Leids Universitair Medisch Centrum (LUMC) nadat artsen hen attendeerden op een patiënt met een moeilijk behandelbare…
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Annemarie Samuels and Liesbeth van Vliet argue in Dutch newspaper Trouw for better conversations about death
In the opinion article ‘Maak praten over de dood niet tot een morele plicht’ (Don’t turn talking about death into a moral obligation) Annemarie Samuels and Liesbeth van Vliet, argue together with Marike de Meij and Sander de Hosson that it is important to have conversations about death and dying but…
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An Online Corpus of UML design models: Construction and empirical studies
Promotores: J. Kok, M. Chaudron (Chalmers University)
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Towards a feminist playology: social sport studies and the limits of critique
The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…
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Superlattices in van der Waals materials: A Low-Energy Electron Microscopy study
n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.
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Studies of dust and gas in the interstellar medium of the Milky Way
Promotor: Prof.dr. A.G.G.M. Tielens, Co-Promotor: J.B.R. Oonk
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Open Science Monitor – Study on Open Science: monitoring trends and drivers
The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets
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How To Be A Historian - Scholarly Personae In Historical Studies 1800-2000
What makes a good historian? When historians raise this question, as they have done for centuries, they often do so to highlight that certain personal attitudes or dispositions are indispensable or studying the past. Yet their vieuws on what virtues, skills or competencies historians need most differ…
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The SAFE study: Suicidal ideation Assessment: Fluctuation monitoring with Ecological momentary assessment
Can we predict fluctuations in suicidal ideation in a person’s daily life, from hour to hour?
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City tales: an art-based participatory framework for studying migration-related diversity (ARTIVES)
The ARTIVES project studies imaginaries of diversity portrayed by artists in Lisbon and Rotterdam in their films, performances and (oral) literature with the aim to explore their transgressive potential of opening up possibilities of thinking differently about migration-related diversity. Their stories…
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In-Forest: A multi-method study of inequality and its epistemic effects in forest research
The project seeks to explore the interplay of valuation and inequalities in science, using the interdisciplinary and planet-critical field of forest research as empirical case. It examines which/whose knowledge is recognised on what grounds, and how social dimensions like gender and geographical location…
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Prijs Henri Pirenne 2023
Om de twee jaar reikt de Koninklijke Commissie voor Geschiedenis de Prijs Henri Pirenne uit. Die prijs bekroont de auteur van een al dan niet uitgegeven belangrijke editie van teksten die betrekking heeft op de geschiedenis van België en als exemplarisch wordt beschouwd. Deadline: 1 juni 2023.
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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Towards Open and Reproducible Terrorism Studies: Current Trends and Next Steps
In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…
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Understanding collaborative governance approaches to ‘big’ problems through studying ‘small’ practices
In this article, Lianne Visser contributed to the understanding of why collaborative governance is a challenging response to wicked problems.
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ASCL Seminar: Hope and uncertainty in African migration - a case study of involuntary return to Ghana
Lecture
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Heritage Education — Memories of the Past in the Present Caribbean Social Studies Curriculum
As part of Nexus 1492 Subproject 4: A Future for Diverse Caribbean Heritages, which seeks to shed light on how local communities interpret and engage with heritage in the present day, this doctoral study aims to gain insight into how indigenous heritage is represented in the school curriculum for social…
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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An ex vivo human skin model for studying skin barrier repair
In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.