The Central and Eastern European Studies Centre is an interdisciplinary platform of scholars of Leiden University. The Centre’s mission is to bundle together, strengthen and disseminate existing research into the history, politics, and culture of the region, spanning the new member states of the EU,…

The Centre for Late Antique and Medieval Studies (LAMS) is an academic initiative housed at the Leiden University Institute of Philosophy. It brings together researchers and academics working on one or more aspects of late antiquity and medieval studies, across the fields of philosophy, history, theology,…

Are you a Leiden University student (thinking of) studying in the UK? Find out more about the impact of Brexit for current and prospective EU students of Leiden University studying abroad in the UK.

Study information

Study information

The Center for Interdisciplinary Placebo Studies Leiden (IPS) aims to advance the understanding of placebo and nocebo effects, their underlying mechanisms, and their potential applications in clinical practice. IPS consists of a group of interdisciplinary researchers working at Leiden University with…

Study information

Study information

With Brill, LUCIS publishes a peer-reviewed book series, “Leiden Studies in Islam and Society” (LSIS), aimed at an international academic audience.

So you've been accepted onto an exchange or study abroad programme at Leiden University. Congratulations! Now it's time to make preparations for your stay.

We are pleased you’ve chosen Leiden University for your study abroad or exchange programme and we look forward to receiving your application.

For Arabic and Islamic Studies and Middle East Studies

For Arabic and Islamic Studies and Middle East Studies

Research in the History and International Studies 1900-present specialisation addresses the interconnectedness and interdependence of contemporary global political, economic and cultural developments from a multidisciplinary perspective which is rooted in the humanities.

This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.

Promotor: A.P. IJzerman

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

On 11 November 2021, Evelien Campfens defended the thesis 'Cross-border Claims to Cultural Objects'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. W.J. Veraart (VU Amsterdam).

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

This volume explores the nature of ellipsis, the core phenomenon that results in various types of omission in sentences.

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Natural product inspired antibiotics to address resistance

Supervisor: Gerard van Westen

Promotor: Prof.dr. M. Ubbink

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Promotor: G.P. van Wezel

Kohei Suzuki is Assistant Professor at Institute of Public Administration. This study carries several important implications for understanding the policy impacts of a graying population and for studies of the welfare state, in general.

Scientific integrity is an essential element in the PhD trajectory and is addressed in several different settings.

Promotoren: G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Neurobiological, cognitive and behavioural measurements of normal and abnormal child development.

Are you thinking about studying Cultural Analysis: Literature and Theory? Learn more and watch the introduction video.

Are you thinking about studying French Literature and Culture? Learn more and watch the introduction video.

Are you thinking about studying Italian Literature and Culture? Learn more and watch the introduction video.

Are you thinking about studying English Literature and Culture? Learn more and watch the introduction video.