Source: Mediators Inflamm (2014)

From scanners in lecture halls to systems for working from home: the discussion about new technology is being held on various fronts. That is why the University wants to make more use of its in-house experts. At the Technology and Trust symposium at Leiden University on 2 February, researchers from…

We are happy that the Media Technology staff and students will together again visit the Ars Electronica Festival in Linz (Austria). The five-day study trip offers a shared source of inspiration and a basis for discussion to students and lecturers.

Global science research serves the needs of the Global North, and is driven by the values and interests of a small number of companies, governments and funding bodies, finds a major new international study published today. As such, the authors find, science, technology and innovation research is not…

We are excited to restart the Media Technology alumni talk series, organized by students, for students and alumni. Upcoming edition will bring us two alumni to share their unique journeys after Media Technology: Ella Keijzer and Bastiaan Terhorst.

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

Searching for ways to delay the need for a transplant and trying to build kidneys to order.

More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

Getting personal

How to understand the simultaneously dis- and reappearance of letters in contemporary culture, and how does this Neo-Epistolarity relate to media-technological change?

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

What are the principles of genome folding and dynamics in bacteria?

Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Promotor: Roeland M.H. Merks

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

List of Support Departments at LION and the Faculty of Science

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Supervisor: P.J.J. Hooykaas

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Eduard Fosch Villaronga, Assistant Professor at eLaw, co-organised together with Aurelia Tamò-Larrieux, Christoph Lutz, Anton Fedesov, and Anto Čartolovni the GoodBrother International Conference on Privacy-friendly and Trustworthy Technology for Society on 28 June 2022 in Zagreb, Croatia.

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

On Friday 12 March 2021, the (Dutch) website www.codevoorkinderrechten.nl was launched. This code for children’s rights has been created to help those involved in the development and design of digital services to develop these services with the interests of children in mind.

It’s not something the police force wants to see, but it still occurs: racist and misogynist police conduct. Human rights specialist Dr Linda Louis has studied how technology could help police officers behave correctly and comply with the applicable legal norms.

This article illustrates how the term 'dual use' has become associated with a broader dichotomy between ‘legitimate’ and ‘illegitimate’ purposes.

Bike Labyrinth is international market leader in providing virtual reality exercising for elderly care.

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Discovery of metastasis promoting candidate drug targets

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Projects within the theme ‘Computational Biology’ aim to employ mathematical or computational dynamical modelling approaches to discover novel concepts that are important for drug development.

The Schengen Agreement has resulted in systematic border controls between EU Member States largely ceasing to apply. Solutions for the associated security risks are often sought in information technology. Tim Dekkers investigated how such technology is applied in this context and will defend his PhD…

Dr. Eduard Fosch-Villaronga, Marie Skłodowska-Curie Postdoctoral Researcher at eLaw, received a personal visiting researcher grant from the Research Council of Norway to spend five weeks visiting the University of Oslo.

On 9 October 2023, Carlotta Rigotti and Eduard Fosch-Villaronga participated in the BIAS webinar on citizen science and AI technologies, namely the first awareness-raising activity of the Horizon Europe BIAS project. They discussed online citizens’ engagement on tackling gender and intersectional biases…

The Conference on Computers, Privacy and Data Protection (CPDP) is an annual world-leading multidisciplinary conference that takes place in January in Brussels. This year, eLaw, the Centre for Law and Digital Technologies of Leiden University, participates in the CPDP conference as one of the event’s…

De discussie over de sluiting van illegale schietbanen van Defensie, als gevolg van de stikstofwetgeving is ingewikkeld en omvat diverse juridische aspecten. Armin Cuyvers, hoogleraar Europeesrecht, bespreekt de zaak in BNR-Nieuwsradio.

The Green algae Chara as model system for intra and inter cellular transport processes.

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.

PhD candidate Karen van den Akker has written a children’s book to get young girls excited about technology. The picture book ‘Met mama naar Mars’ tells the story of Luna, who wants to travel to Mars.