1,547 search results for “policy evaluation” in the Public website
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Security in Transnational Spaces
This book focuses on transnationalism as a key concept to evaluate how Europe responds to cross-border security challenges.
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Unraveling the Neural Basis of Self-Esteem in Adolescent Depression
What are the social and neural mechanisms that contribute to fluctuations in self-esteem in healthy adolescents and adolescents with depression?
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XXY versus autism: evidence from neuroimaging
Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI
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Vox Populi, Populism as a Rhetorical and Democratic Challenge
This timely and engaging book examines the rise of populism across the globe. Combining insights from linguistics, argumentation theory, rhetoric, legal theory and political theory it offers a fully integrated characterization of the form and content of populist discourse.
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Assessment of monitoring tools and strategies safeguarding aquatic ecosystems within the European water framework directive
CML report 192
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Real-time foresight: preparedness for dynamic innovation networks
Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer
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Postdoctoral Research
It is essential for researchers to be able to obtain independent research funding in order to advance in their career.
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Gemeente Leiden: Water and Climate Change. Climate Proofing Industrial Estates
Climate Proofing Industrial Estates: Entrepreneurs’s Participation in the City of Leiden
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Dosing considerations for preterm neonates: from pharmacometrics to clinical practice
Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.
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Oxidation of Therapeutic Proteins and Peptides: Structural and Biological Consequences
Oxidation is a common degradation pathway that affects therapeutic proteins and peptides during production, purification, formulation, transportation, storage and handling of solid and liquid preparations. In the present work we review the scientific literature about structural and biological consequences…
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A sense of society
This dissertation examines how we can reconstruct physical activity by looking at variations in the shape of muscle attachment sites ( ‘entheses’) on the human skeleton. It evaluates two post-medieval contexts; rural Middenbeemster and urban Aalst.
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Impaired barrier of inflammatory skin diseases
Focus in skin research
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Digging in documents: using text mining to access the hidden knowledge in Dutch archaeological excavation reports
The archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES), which combines full text search with entity and geographical search.
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Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines
Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)
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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)
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Countering Terrorist Narratives: Assessing the Efficacy and Mechanisms of Change in Counter-narrative Strategies
This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…
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Multiway Analysis
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Information for students
General information
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Valuing Landscape in Classical Antiquity. Natural Environment and Cultural Imagination
Different ways in which physical environments impacted on the cultural imagination of Greco-Roman antiquity.
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Normering en toezicht in de opsporing
On 18 November 2020, Mojan Samadi defended her thesis 'Normering en toezicht in de opsporing'. The doctoral research was supervised by Prof. J.H. Crijns.
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Legal Empowerment of Pollution Victims in China and Indonesia
A political-legal study of rights invocation by pollution victims in China and Indonesia
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.
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Una Isla, Dos Mundos
The arrival of Columbus to the Caribbean in 1492 marked a milestone in world history. In both the European and the indigenous world, a set of economic, political and hierarchical networks and relations were defined, structured and changed. These changes affected the indigenous population at different…
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst
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Lithium-ion batteries and the transition to electric vehicles
The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.
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Exploring strange new worlds with high-dispersion spectroscopy
Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…
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Science Communication & Society
The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.
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PLATO
Platform Opleiding, Onderwijs en Organisatie Ltd (PLATO). PLATO is committed to learning, learning in schools, learning in work environments, learning in life and life.
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Lone Actor Terrorist Attack Planning and Preparation: A Data‐Driven Analysis
This article provides an in‐depth assessment of lone actor terrorists’ attack planning and preparation.
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United in incoherence – Private law concepts under pressure from European financial law
Just published: United in incoherence – Private law concepts under pressure from European financial law (in Dutch), in: Tijdschift voor privaatrecht 2017-4
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Nanoparticles
Leiden University has developed a radically different method for large scale production of diverse nanoparticles and their alloys.
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Remote prototype labs and student engagement and achievement in higher education
How do learners engage during project-based learning (PBL) and what is the impact of PBL on their learning outcomes?
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The @school project
Developmental considerations in the design and delivery of cognitive-behavioural therapy for adolescent school refusal
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Episcopal social networks and patronage in late antique Egypt: Bishops of the Theban region at work
The proposed research project examines the social role of two monk-bishops in seventh-century Egypt, Abraham of Hermonthis and Pesynthios of Koptos, by reconstructing their social networks on the basis of their archival documents.
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Political Memory in and after the Persian Empire
An interdisciplinary study of the Persian Period
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D-lightful Sunshine Disrupted
This study stresses the importance of investigating vitamin D deficiency in every community to better understand the deteriorating effect that sociocultural practices may have had on health.
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Graphing formulas by hand to promote symbol sense: Becoming friends with algebraic formulas
In this research we have studied how teaching graphing formulas by hand (i.e. sketching a graph of a formula) could promote grade 11- and 12-students’ symbol sense.
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Efficacy of Self-management training in adolescents and adults with Klinefelter syndrome (XXY)
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OPERA – Open Research Analytics
OPERA aims at establishing open and advanced research analytics practices and systems at Danish universities and in the Danish landscape of research analytics stakeholders.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Social Anxiety and Specific Phobia in youth
Welcome to the Social Anxiety and Specific Phobia (SASP) Research Group!
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Contributions to the phylogeny of the haplolepideous mosses
The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…
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Submissions
Psychoeducational Assessment, Intervention and Rehabilitation (PAIR) publishes high quality articles on theoretical and empirical research regarding psychological and psychoeducational assessment, intervention, and rehabilitation in all areas related to cognitive and socio-emotional development.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Beginsel en begrip van verdeling
On 22 November 2018, Teico Sikkema defended his thesis 'Beginsel en begrip van verdeling'. The doctoral research was supervised by Prof. mr. W.G. Huijgen and Prof. dr. F. Sonneveldt.
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Digiuseppe & Poast, ‘Arms versus Democratic Allies’
In theory, states can gain security by acquiring internal arms or external allies. Yet the empirical literature offers mixed findings: some studies find arms and allies to be substitutes, while others find them to be complements. Political scientists Matthew Digiuseppe (Leiden University) and Paul Poast…