3,266 search results for “parkinson s disease” in the Public website
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Grant: Dr. Amanda Foks receives a prestigious Junior Postdoc fellowship from the Dr. E. Dekker stipendium awarded by the Dutch Heart Foundation
Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
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Automatic analysis of chest CT in systemic sclerosis using deep learning
PhD defence
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Government, media and citizens: Watch out for the nocebo Corona effect
We are confronted on a daily basis with news about the Corona virus and its consequences. We read alarming headlines like 'Dutch becoming increasingly anxious about Corona virus' or 'Huge fears and stress about Corona crisis'.
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From stress to success: Vici grant for Dennis Claessen
Why do some bacteria lose their protective cell wall under the influence of stress? Microbiologist Dennis Claessen of the Institute of Biology Leiden receives a Vici grant of 1.5 million euros from the Dutch Research Council (NWO) to investigate this paradoxical feature.
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First guidelines for applying placebo effect in clinical practice
It is becoming increasingly clear that the placebo effect has a great influence on medical treatment. An international, interdisciplinary team of researchers led by Professor of Health Psychology Andrea Evers from Leiden University has now written a first set of guidelines on how to apply the placebo…
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We all BENEFIT: The Ecosystem for Healthy Living
The modification of risk factors and related health behaviors lies at the very core of adequate cardiovascular risk management, yet evidence shows that the majority of people with cardiovascular disease (CVD) fail to achieve a healthy lifestyle in the long term. The main objective of this project is…
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e-Coach: Tailored cognitive-behavioral e-Health care for patients with chronic somatic conditions
The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.
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Advanced MRI-markers of cerebral small vessel disease
PhD defence
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Multifaceted role of the complement system in health and disease
PhD defence
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Early diagnosis and management of celiac disease in childhood
PhD defence
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4D-Flow MRI of Aortic and Valvular Disease
PhD defence
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Genetics and Life Course Epidemiology of Cardiometabolic Disease
PhD defence
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Atherosclerotic cardiovascular disease: Interplay between sex, age, and circadian rhythms
PhD defence
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Viral gene therapy approaches for CRB1 retinal disease
PhD defence
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Pharmacotherapy and Ventilatory Control in Health and Disease
PhD defence
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Role of intestinal microbiota in cardio-metabolic disease
PhD defence
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Oxidants and antioxidants as targets for cardiovascular disease prevention
PhD defence
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Developmental cell lineage dynamics in Bicuspid Aortic Valve disease
PhD defence
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Disentangling the relationship between depression, obesity and cardiometabolic disease
PhD defence
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Single-cell mechanics for disease biology and pharmacology
PhD defence
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What's China's comment?
On the 25th of February, Peng Wu successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Peng on this achievement.
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Healthy elderly in clinical trials: how to define preclinical Alzheimer’s Disease for clinical trial participation
PhD defence
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Annemarie Meijer new training coordinator in European network
The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.
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On imagination in science: ‘A good researcher is also an inventor’
As far as Daniël Pijnappels, Professor of Cellular Electrophysiology, is concerned, both researching and inventing are essential for a scientist.
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Healthy food, healthy world
What does it mean to eat healthily and responsibly? This question is gaining a new urgency now that in many countries undernourishment is being overtaken by diseases of affluence, such as obesity, and we are also becoming more aware of the environmental impact of our eating habits. It’s time to take…
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Japan
This is an Erasmus+ International Credit Mobility project of the Leiden University Medical Center with Nagasaki University.
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Research
An overview of the research at the Biologics Formulation group
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Repair a bad kidney or make a new one to order
Searching for ways to delay the need for a transplant and trying to build kidneys to order.
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Science for Society
By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Leiden Institute of Chemistry
The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.
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Computational Drug Discovery
Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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Biomedical Sciences (MSc)
In this master programme you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme Biomedical Sciences relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…
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Gravitation funding for five projects with Leiden researchers
The Advanced Nano-electrochemistry Institute Of the Netherlands (ANION) consortium will receive 23.6m euros in Gravitation funding for research on important electrochemical processes for energy transition. An additional four consortia with members from Leiden have also been awarded funding.
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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Algorithm for Structural Variant Detection
Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.
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Faculty Teams (FAiMs)
We encourage you to contact your faculty Academia in Motion team (FAiM). Each faculty team translates AiM's principles and activities to their own unique needs and context.
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Vascular and Regenerative medicine
With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Imaging
The imaging group focuses on bio-imaging, image analysis and visualization.
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Bioactive Molecules
Bioactive Molecules is one of the four research themes of the Institute of Biology Leiden.
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IBL Spotlights
During the IBL Spotlights, researchers of our department discuss their newest findings and achievements. After the lectures, you are all invited to the reception on the first floor of the Sylvius building.
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Technical Medicine (MSc)
Leiden University offers a unique interdisciplinary joint-degree Master programme in technical medicine together with TU Delft, Erasmus University Rotterdam and their academic medical centers.
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T-DNA integration and DNA repair of DSBs in plants
Identification and characterization of components of DNA repair pathways and their role in Agrobacterium T-DNA integration and repair of CRISPR/Cas induced DSBs.
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Microbial Induction of Plant Resilience to Drought Stress (MicroRes)
What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?