1,640 search results for “evaluation” in the Public website
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Host community compensation
Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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Economic thinking in the Socratic authors and Aristotle
This subproject of 'From Homo Economicus to Political Animal' analyzes Greek economic thinking in late 5th- and 4th-century philosophical circles.
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Reading Rubbish
Using object assemblages to reconstruct activities, modes of deposition and abandonment at the Late Bronze Age dunnu of Tell Sabi Abyad, Syria.
- Integration in Urban planning
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Jus Post Bellum
Jus post bellum, the body of laws and norms governing the transition from armed conflict to peace, has emerged as a crucial issue for international law scholars, governments, and all concerned with building a just and sustainable peace. The Jus Post Bellum Project, funded by the NWO and hosted by the…
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Multilevel governance and responses to the COVID-19 pandemic: a systematic literature review
In this article, the authors summarise the literature on the effects of multilevel governance on governments’ policy responses to Covid-19.
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Guidelines for reviewing
The refereeing process is anonymous. It is important, therefore, that all submissions conform to the above guidelines. The referees’ comments will, at the Editor’s discretion, be passed on to the corresponding author.
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EU-STRAT: ‘The EU and Eastern Partnership Countries: An Inside-Out Analysis and Strategic Assessment’
What should the EU do to support Ukraine, Belarus and Moldova? How can the European Union adapt its policies towards these countries in a very difficult and challenging geopolitical context?
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COMMUNICATE HEAL-TH. A Virtual Reality training tool for optimizing expectancy effects in patient-provider interaction.
We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.
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General plant strategies and functions in wetlands: Global trait-based analyses
Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.
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Cyber Governance and National Security: Intervening in Ungoverned Spaces
The Netherlands Ministry of Defense and Ministry of Security and Justice have requested the Centre for Terrorism and Counterterrorism to complete a research project on cyber governance from a policy perspective. The results of this project will contribute to the deliverables of the fourth International…
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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CWTS
The Centre for Science and Technology Studies (CWTS) is an interdisciplinary research institute at Leiden University that studies scientific research and its connections to technology, innovation, and society.
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HazMat transportation safety assessment: Analysis of a “Viareggio-like” incident in the Netherlands
Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…
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Cyclophellitol analogues for profiling of exo- and endo-glycosidases
To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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Magnetic Resonance Microimaging of Alzheimer's Disease
Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…
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Research
The members of LUXs develop and validate new methods and algorithms for analysing data, and apply these in a wide range of problems. Their research ranges from multidisciplinary applications to proving mathematical theorems.
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Traces of language contact: The Flores-Lembata languages in eastern Indonesia
On the 13th of November, Hanna Fricke successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Hanna on this achievement.
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Learn to Dare!
The ‘Leer te Durven!’ program (Learn to Dare) is a preventive training program for children with mild anxiety symptoms (Simon & Bögels, 2014). The program has been developed for children between the ages of 8 and 12 who feel or behave anxiously, avoid situations, are afraid of doing things wrong, appear…
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The Informed Performer- Towards a bio-culturally informed performers’ practice
Playing a musical instrument is generally considered to be a complex human behaviour involving the integration and coordination of a broad range of human functions such as perception, imagination, memory, information processing, emotion, communication, and dexterity.
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Targeted Informed consent: empowering young participants in medical-scientific research
Promotor: J.M. van den Broek Co-promotor: M.C. de Vries
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Personal experience narratives in three West African sign languages
On the 27th of February, Marta Morgado successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Marta on this achievement!
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
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Technological innovation in neuropsychology
Technological advances, such as virtual reality, augmented reality and online assessment platforms are rapidly improving. These tools could potentially contribute to neuropsychological assessment that is more efficient and of higher quality.
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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Editorial: Sanity and Resilience in Times of Corona
This editorial to RHCPP discusses how COVID-19 can be seen as a 'creeping crisis' according to the authors of its lead article (Boin et al, 2020) and how resilience may depend on the real heroes behind the scenes of response to disaster and adversity.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Citizen Science
From where litter ends up to which languages are spoken in Leiden and The Hague: over 50 interesting, surprising, complex and entertaining questions were sent in for the Citizen Science project to mark our 444th anniversary. Not one but two Citizen Science projects will be starting this year in Leiden…
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An anthropological rethinking of the Pintados and early tattooing in the Visayas, Central Philippines
In this paper, Andrea Malaya M. Ragragio and Myfel D. Paluga recast new light on the historical tattooing of the “Pintados,” or the the name by which the inhabitants of the Visayas Islands (in the central Philippines) were called by Spanish documenters in the sixteenth century. This is one of their…
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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Spinoza's Theory of Religion: The Importance of Religion in Spinoza's Thought and Its Implications for State and Society
On 23 October 2019, Yoram Stein defended his thesis 'Spinoza's Theory of Religion: The Importance of Religion in Spinoza's Thought and Its Implications for State and Society'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. A.A.M. Kinneging.
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Assessor-Centered Translation Quality Assessment: A Theoretical Model and a Case Study
Behrouz Karoubi defended his thesis on 15 June 2016
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Clinical Psychology
Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.
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RISIS – Research infrastructures for the assessment of science, technology and innovation policy
The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…
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Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetic models
Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen
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Programme structure
The master's specialisation Occupational Health Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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Programme
This summer school will explore the concept of socioeconomic diplomacy in the context of global empire building (16th-19th centuries).
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Study programme
The IEG specialisation prepares you with knowledge and understanding of the key concepts and theories of management, decision-making processes and implementation in EU and international institutions.
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International Organisation (MSc)
This specialisation focuses on the interplay of international rules and institutions, non-governmental organisations, and national governments in an era of emerging powers, technological change and pressing issues of security, prosperity and sustainability.
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Student projects
Are you looking for a research project? We have projects available for motivated 6–9-month internship students with particular interest in organic/polymer synthesis, formulation development, gene delivery, protein delivery, and the preliminairy in vitro screening of drug delivery platforms. Students…
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Bilingual lectures on Sign Languages and Deaf Studies
Open access, online talks on African Sign Language Studies, in International sign and English
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From standard pots to potters' standards
An integrated approach to ceramic standardization and change in Archaic Satricum (6th–4th century BC)
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The Politics of Policymaking: An Introduction
Never has good policy been so important. From unemployment and a lack of affordable housing to regulating cryptocurrencies and protecting against cybersecurity threats, the challenges we face are complex and global. The text explains how policymaking works: from the emergence of policy ideas to deciding…
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Research
The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.