263 search results for “gene theory” in the Staff website
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live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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Advocating for gene therapies for rare diseases
‘If we don’t start talking about this, who else will?’ This is what Arjan Lankester, paediatrician/immunologist at the Leiden University Medical Center (LUMC) and Professor of Paediatrics, thought when it seemed that various extremely effective gene therapies for rare diseases would no longer be available…
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Charlene KalleScience
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Luca AvenaScience
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Michael KeaneScience
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Floske SpieksmaScience
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Evgeny VerbitskiyScience
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Kyra AlbertsFaculty of Humanities
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Koenraad SchalmScience
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Frank den HollanderScience
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Evert Jan van LeeuwenFaculty of Humanities
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Georgios-Evgenios DouliakasFaculty of Humanities
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René van der Veer
Faculteit der Sociale Wetenschappen
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Zhong ChuaFaculty of Humanities
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Theory of Mind in Language, Minds and Machines: a Multidisciplinary Approach
PhD defence
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Ronald CramerScience
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Marco StrengScience
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M BhargavaScience
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Peter BruinScience
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Megumi KitagawaFaculteit der Sociale Wetenschappen
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Rebecca PloofFaculteit der Sociale Wetenschappen
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Mariëlle Linting
Faculteit der Sociale Wetenschappen
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Hendrik LenstraScience
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David HolmesScience
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Martin BrightScience
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Rusydi MakarimScience
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Peter StevenhagenScience
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Major international study links genes to brain structural changes over time
There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Jan-Hendrik EvertseScience
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Robin de JongScience
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Ronald van LuijkScience
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Bart de SmitScience
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Ernst van AlphenFaculty of Humanities
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Hendrik KapteinFaculteit Rechtsgeleerdheid
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Francisca JungslagerFaculteit der Sociale Wetenschappen
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Richard GillScience
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Jeroen ten VoordeFaculteit Rechtsgeleerdheid
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Rob TijdemanScience
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Matthew LongoFaculteit der Sociale Wetenschappen
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Chenyu ShiScience
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Carlos Roos MuñozFaculty of Humanities
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Arash MohammadavvaliFaculty of Humanities
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Mateo CohenFaculteit der Sociale Wetenschappen
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Nidesh LawtooFaculty of Humanities
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Priyanka ChopraScience
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Merijn de BakkerScience