8,335 search results for “publication” in the Public website
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Contribute
The editorial board of Inter-Section happily invites contributions from ambitious archaeology students, or recent graduates, of Leiden University’s Faculty of Archaeology. We welcome all sorts of article submissions, as long as they are based on the original work of the author and contribute to the…
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Sustaining the unsustainable? The political sustainability of pensions in Finland and the Netherlands
What makes a pension scheme sustainable? Most answers to this question have revolved around expert assessments of pension schemes’ affordability or adequacy. This study shifts focus from the financial or social sustainability of pension scheme designs to their political sustainability. The key question…
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Looking Beyond Our Similarities
How Perceived (In)Visible Dissimilarity Relates to Feelings of Inclusion at Work
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Centre for Digital Heritage (CDH)
The Centre for Digital Heritage undertakes collaborative international research in the field of Digital Heritage. It is an initiative of the University of York.
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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
The potential of bioneedles to deliver influenza vaccines was investigated.
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Ethics and copyrights
PAIR stands for ethical publishing and transparency. Below you can read about our commitment to COPE principles, copyright compliance and rigorous peer review ensures the integrity of every article we publish.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Embracing the Provinces: Society and Material Culture of the Roman Frontier Regions
Embracing the Provinces is a collection of essays focused on people and their daily lives living in the Roman provinces, c. 27 BC-AD 476. It offers an overview of current research on Roman provinces and frontiers, deconstructing some long-held preconceptions and providing refreshing insights into unexplored…
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.
- Ostia Speaks
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Development of cross-protective influenza A vaccines based on cellular responses
Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Negotiating Peace with Your Enemy: The Problem of Costly Concessions
Why do some parties fail to settle conflict, even after long periods of fighting? ISGA PhD candidate Valerie Sticher suggests that costly concessions often stand in the way of a negotiated agreement. Conflict party members not only care about their in-group's welfare, but also want to avoid rewarding…
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Windmills of the Mind: Higher-Order Forms of Disinformation in International Politics
James Shires has contributed a chapter to the proceedings of the 13th International Conference on Cyber Conflict (CyCon 2021), which gathers 20 articles from the law, technology and strategy domains.
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Characterization and skin permeation of ketoprofen-loaded vesicular systems
PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.
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A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits
Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)
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Combining Participatory Mapping and Geospatial Analysis Techniques to Assess Wildfire Risk in Rural North Vietnam
Andrea Bartolucci is Assistant Professor at Institute of Security and Global Affairs. In this study, the scholars adopted a multidisciplinary approach to investigate wildfire risk in Van Chan district in northern Vietnam, a region where official data are sometimes difficult to collect or inconsisten…
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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Why bother? Local bureaucrats’ motivations for providing social assistance for refugees
The author researched the motivations of bureaucrats to integrate refugees into welfare services even when they do not have any legal obligation to do so.
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Research
Research at the Grotius Centre for International Legal Studies is primarily carried out under its Research Programme ‘Exploring the Frontiers of International Law’.
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Establishing State Responsibility in the Absence of Effective Government
On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'.
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Measurement of the average mass of proteins adsorbed to a nanoparticle by using a suspended microchannel resonator
SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.
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Spectacle and Surveillance: The Making and Unmaking of Collective Visual History
What is the iconography of propaganda specifically as it relates to the historical development of political ideologies in modern Egypt and how was/is this propaganda disseminated among creative fields such as cinema, art, monuments, architecture, and literature?
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A sustainable environment
Making public space more sustainable is considered very important in this project. The Humanities Campus will become a pleasant place to spend time, with lots of greenery. Here, people can relax and find coolness on hot summer days.
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Research
Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.
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Beyond UN75: A Roadmap for Inclusive, Networked & Effective Global Governance
Drawing on insights from past and contemporary scholars and world leaders, the report explores the concepts of a new social contract, a new global deal, and networked and inclusive multilateralism introduced recently by Secretary-General António Guterres to help the United Nations better grapple with…
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Addressing loneliness and social isolation amongst elderly people through local co‐production in Japan
Loneliness and social isolation have become a significant problem in contemporary Japan. The financial burden associated with an ageing population has severely constrained the ability of local authorities to address the problem. As a result, policymakers have sought cost‐effective methods of tackling…
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Formative Assessments and Teacher Professional Learning
How can formative assessment be used to promote teacher professional learning? This book contains various studies into professionalization approaches and courses in which formative assessment is used with a view to teacher learning.
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Leiden Center for the Study of Ancient Arabia
The Leiden Center for the Study of Ancient Arabia aims to promote research on the ancient languages and cultures of Arabia, and to disseminate this knowledge to the broader public.
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ZonMw – Optimizing the responsible researcher: towards fair and constructive academic advancement
Researchers are pulled in various, sometimes contradictory directions by the multiplication of performance metrics and new incentives to align with societal needs. Management structures, funding systems, and publication practices are increasingly influenced by pressures to promote only the highest quality…
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Citizens, Elites, and the Legitimacy of Global Governance
Jan Aart Scholte, Professor Global Transformations and Governance Challenges, is a co-author of this book that offers the first full comparative study of citizen and elite legitimacy beliefs toward global governance.
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Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
Source: J Cheminform, Volume 7, Issue 1 (2015)
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).
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Health and the social investment state
Recent years have seen a vibrant scholarship on health policy and politics. While much is now known about changes to health policies and institutions over time, this study finds that scholarship still lacks research on the linkages between health policies and health outcomes (Marmor & Wendt, 2012).…
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A renewed awareness: Reinvigorating preparedness research for crisis and disastermanagement
In this article Jeroen Wolbers and Sanneke Kuipers take a closer look at disaster preparedness to reinvigorate the academic debate.
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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Politics, Culture and National Identities 1789-present
Politics, Culture and National Identities investigates a wide range of national political cultures in Europe and the Americas in the 19th and 20th centuries.
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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PAIR: The Journal
PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.
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UN, EU, and NATO Approaches to the Protection of Civilians: Policies, Implementation, and Comparative Advantages
The protection of civilians (POC) in armed conflict has become a core strategic objective for the United Nations system and for UN peace operations in particular. The UN, however, is not the sole actor engaged in POC.
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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation
Source: PLoS ONE, Volume 10, Issue 3 (2015)
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Protein-polyelectrolyte interactions: Monitoring particle formation and growth by nanoparticle tracking analysis and flow imaging microscopy
The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.
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Blended Care for Adolescents with Social Anxiety
Is blended care a feasible and effective treatment method for social anxiety in adolescence?
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Queer Salon, bringing together insiders and outsiders
Doctoral research on the history of the critical visitor and their efforts at founding alternative archives including LGBT+-focused, feminist, disability and digitizing projects, resulting in a traveling exhibition on findings (with audio-guides), popular and scholarly article, and a dissertation.