3,486 search results for “research with animal” in the Public website
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Responsible research with animals
Animal experiments are not undertaken lightly; we are working with sentient beings. As scientists, we have great responsibility to handle laboratory animals with care. Read here how we consider and justify this.
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FAQ research with animals
Antwoord op veelgestelde vragen over onderzoek met proefdieren bij de Universiteit Leiden. FAQ
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Research with animals
At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.
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Nelleke Verhave
Science
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Education and training on animal experiments
Our scientists working with laboratory animals undergo training on animal experiments. In this training, researchers learn how to handle laboratory animals responsibly. Read more about the requirements we set for researchers working with laboratory animals.
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Animal-free chemical safety testing with new technology ToxProfiler
Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…
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Laboratory animal facilities
We have facilities for various research animals, all of which naturally comply with legal requirements. We take great care of the animals, and our enclosures are designed to meet the specific needs of the different species.
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Why stress could be good for you
Acute stress seems to have a surprisingly positive effect on our health. Researcher Erin Faught received an NWO veni grant to find out why that is and how we can use that knowledge to our advantage. For her lab research, she uses a remarkable small animal to learn more about our own stress levels.
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Why you should publish negative data
As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society…
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How light and noise pollution disrupt aquatic life
Fish populations in lakes and rivers have declined in recent decades. This is probably due to light and noise pollution. The Horizon Europe grant enables ecologist Hans Slabbekoorn to investigate this and improve the situation for migrating fish. In order to do so, a seven-metre-long swimming tunnel…
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Robo-bird teaches young zebra finches to sing
How do young zebra finches learn to sing? A research team led by researcher Katharina Riebel has developed a ‘RoboFinch’ to study just that. She and colleagues in the 'Seeing voices' research consortium have spent the past four years designing the robotic bird. And with success: young zebra finches…
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A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
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Assessing the safety of chemicals and medicines without laboratory animals
One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.
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JLGC 08: Animals (Un)tamed: Human-Animal Encounters in Science, Art, and Literature
The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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New treatments for life-threatening disease sepsis
Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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The Case against Animal Rights: A Literary Intervention
This thesis aims at thinking through the ethical position of animals in a way that differs radically from the manner in which this ethical position is thought within contemporary animal rights discourse.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Responsible animal testing
Within Leiden University, we sometimes conduct research with laboratory animals. We only do this when when we cannot answer the research question in any other way.
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Animal welfare
We carry a profound responsibility for our research animals and strive to provide them with the best possible quality of life. In our studies, we make every effort to avoid and minimise discomfort for the animals. Below, you can learn more about how this is put into practice.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Animals and Liberal Democracy
What does the interspecies interpretation of the equality principle mean for the liberal democracy, and is it possible to provide for an appropriate legal and political position for animals without defying the classic-liberal principles of the liberal democratic state?
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Animal models for cutaneous vaccine delivery
Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.
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Animal Welfare Body Leiden (AWB)
The Animal Welfare Body Leiden (AWB) is an internal entity responsible for the well-being of all laboratory animals at Leiden University and the Leiden University Medical Center. It is actively involved in all aspects of research involving animals. The AWB has several legal responsibilities, including…
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Alternatives to animal experiments: Replacement, Reduction and Refinement
We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…
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Changing Patterns of Animal Exploitation
This part entails the analysis of an extensive sample of animal bone (c. 30,000 pieces) retrieved from well-defined archaeological contexts of the early period at Tell Sabi Abyad, c. 6800-6200 BC. It comprises aspects of taphonomy, ageing and osteometry, the reconstruction of the local spectrum of domestic…
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Development & Disease in Animal Sciences
Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.
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Adaptation, Discretion, and the Application of EU Animal Welfare Legislation
Brendan Carroll promoted On Thursday October 30th Brendan Carroll successfully defended his PhD dissertation entitled:
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Evolution & Biodiversity in Animal Sciences
Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.
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Central Animal and Transgenic Facility
Keeping and breeding of test animals for the purpose of scientific research and education.
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.
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The use of animal manure by prehistoric and early medieval farmers
Did early farmers deliberately use animal manure on their fields?
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The Open Society and Its Animals
On 10 October 2019, Janneke Vink defended her thesis 'The Open Society and Its Animals'. The doctoral research was supervised by Prof. P.B. Cliteur.
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Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
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The variational mode: three cases about documents, artworks and animation
My artistic practice deals with documents and, more specifically, with the use and the exploration of their narrative potential.
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Lightning Pose: improved animal pose estimation
Science begets technology but technology also begets science. Anne Urai from the Leiden Institute of Psychology is part of an international team team that rolls out a new, user-friendly, plug-and-play AI tool they hope will become an engine of discovery by quantifying the growing volume of recorded…
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Screening of animal venoms for antimicrobial compounds
Can animal venoms yield novel antimicrobial peptides?
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Host-Microbe Interactions in Animal Sciences
Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.
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Indigenous animal management practices on the eve of Columbus' landfall
Isotopic and zooarchaeological investigations in the Dominican Republic and Jamaica
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Emancipation in Postmodernity: Political Thought in Japanese Science Fiction Animation
Mari Nakamura defended her thesis on 14 March 2017
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Species Literacy: The perception and cultural portrayal of animals
In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.
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Animals in Dutch Travel Writing, 1800-present
Apart from humans, animals play a pivotal role in travel literature.
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Jiangnan Sun
Science
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From Homo Economicus to Political Animal
Who is Economic Man? Every economic paradigm presupposes an anthropology, a theory of human nature. This project explores the anthropologies presupposed and produced by ancient Greek economic texts, and the specific knowledge forms that shape these anthropologies.
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Minipigs as an Animal Model for Dermal Vaccine Delivery
Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.