91 search results for “metabolic nanoparticles” in the Staff website
-
Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
-
The effect of nanoparticles on our planet
‘Solar panels, toothpaste and sport socks. What do these things have in common?’ Martina Vijver, professor of ecotoxicology begins her TEDx-talk. Watch her online lecture if you want to learn more about the effects of nano-particles on our environment and health.
-
Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
-
Special nanoparticles for cancer therapy! Will you help?
Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.
-
How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
-
Lennart Schada von BorzyskowskiScience
-
Alexa SchrickelFaculteit der Sociale Wetenschappen
-
Hans AertsScience
-
Camille SouamaFaculteit der Sociale Wetenschappen
-
Rik MomScience
-
Nanoparticles: shapeshifters that pass along the food chain and end up in the brain
Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…
-
Leiden Scientists: 'Environmental risks of new pesticides with nanoparticles insufficiently examined'
The environmental risks of new pesticides containing nanoparticles are inadequately researched, according to four Leiden scientists in the scientific journal Environmental Science & Technology. They call for an examination of the long-term and environmental effects of pesticides containing nanoparti…
-
Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
-
What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
-
Eline DekeysterFaculteit der Sociale Wetenschappen
-
Miranda van EckScience
-
Aleksandrina SkvortsovaFaculteit der Sociale Wetenschappen
-
Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
-
Irene GrootScience
-
Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
-
Sandra IrmischScience
-
Phase Separation in Lipid-based Nanoparticles
PhD defence
-
Photothermal circular dichroism studies of single nanoparticles
PhD defence
-
Developmental effects of polystyrene nanoparticles in the chicken embryo
PhD defence
-
mRNA and Drug Delivery with Lipid-based Nanoparticles
PhD defence
-
Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
-
Studies on molecular basics of metabolic syndrome in zebrafish
PhD defence
-
Ecology and genomics of Actinobacteria and their specialised metabolism
PhD defence
-
Tomer FishmanScience
-
Robert VerpoorteScience
-
Shiza AslamScience
-
Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design
PhD defence
-
Can we make bioplastics with artificial photosynthesis?
Mimicking photosynthesis to produce bioplastics sustainably and efficiently. Researchers from the Institute of Biology Leiden (IBL) and the Leiden Institute of Chemistry (LIC) will assess this new approach. ‘An exciting opportunity to explore a new, appealing research topic in a collaboration between…
-
Modelling the Interactions of Advanced Micro- and Nanoparticles with Novel Entities
PhD defence
-
EUniWell Open Lecture Series | Metabolic trajectories before the diagnosis of type 2 diabetes
Lecture, Lecture part of a series
-
Toxicity, bioaccumulation and trophic transfer of engineered nanoparticles in the aquatic environment
PhD defence
-
integration with genome-scale modelling of dopaminergic neuronal metabolism
PhD defence
-
Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
PhD defence
-
Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
PhD defence
-
The development of molecular tools for investigating NAD+ metabolism and signalling
PhD defence
-
Quantitative and miniaturised assays for structure-resolved lipidomics in metabolic disease
PhD defence
-
Exploring the metabolism and toxicity of amino sugars and 2- deoxyglucose in Streptomyces
PhD defence
-
Elena EgorovaScience
-
Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
-
Chao DuScience
-
Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
-
Polypeptide Therapeutic Solutions and Universiteit Leiden Announce Collaboration to Develop Advanced Polyaminoacid Drug Delivery Systems
Polypeptide Therapeutic Solutions (PTS), a leader in the design, development and custom manufacturing of polyamino-acid based delivery systems for therapeutic drugs and the Leiden Academic Centre for Drug Research (LACDR) today announced a research collaboration to develop advanced drug delivery systems…
-
Driven by curiosity: master student Linde Schoenmaker publishes review paper about COVID-19 vaccine stability
During her search for a subject for the literature study of the Bio-Pharmaceutical Sciences master programme, Linde Schoenmaker read a press release about the ultra-low storage temperatures of the COVID-19 vaccines. She wondered why these vaccines must be stored at such cold conditions. Her question…
-
Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
-
A high protein diet may accelerate atherosclerosis
A widely publicized research article in Nature Metabolism by scientist from the University of Pittsburgh, suggests a high protein diet which is popular among for instance fitness enthusiasts, may be harmful to the cardiovascular system. National media outlets such as NRC Handelsdagblad and NPO 1 Radio…