1,285 search results for “patients” in the Public website
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Leiden statisticians create app for patients and doctors to calculate cancer survival probabilities
A new app is able to calculate personalised survival probabilities for patients suffering from soft tissue sarcoma. Doctors and patients can use the app to calculate personalised survival probabilities together. Mathematician Anja Rüten-Budde received her doctorate for her research into survival probability…
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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Exposure therapy also helps patients with childhood trauma process the past
Childhood trauma can have a lifelong effect. Many therapists do not dare to confront these vulnerable patients with their past because they are concerned that the patients will be unable to cope. Research has now shown that exposure therapy can be helpful for this group of people.
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Using VR to experience how it feels when a patient throws a shoe at you
Psychology students usually only get to meet patients very late in their studies. Therefore, neuroscientists Ineke van der Ham and Judith Schomaker want to research whether students learn more effectively from a virtual experience with a patient with dementia than from a text. Schomaker: 'We have plans…
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Headache e-diary aimed at more personalised help for patients and physicians
Funded by a ZonMw grant, the LUMC and the Health Campus The Hague will be working with headache patients on research into the use of an electronic headache diary. This resource can help patients gain a better understanding of their migraine attacks and, together with the physician, produce the best…
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Leiden’s poo can help rid patients of resistant gut bacteria
Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).
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Putting migraine into words: the patient’s account is crucial for diagnosis
Migraine can’t be diagnosed with a blood test, scan or physical examination. Language therefore plays a crucial role in its diagnosis. Neurologist Joost Haan has researched the relationship between language and migraine, and looked at how migraine is described in fiction. His PhD defence is on 22 Oc…
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PhD candidate has patients barking up the wrong tree with virtual reality
People with intermittent arterial claudication often experience severe pain when walking. Psychologist Anne Cuperus used virtual reality to trick 20 patients, and discovered that they could suddenly walk much further. PhD defence on 10 December.
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Care conferences for long-term forensic patients: demand greater than supply
Care conferences for long-term residents (15+ years) in forensic mental health care are widely appreciated by all parties involved. Research by Leiden University shows that the demand for these meetings is so great that the supply cannot be met within the desired time frame.
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Medical Delta professor Lioe-Fee de Geus-Oei: 'We work together for the patient'
Professor of Radiology Lioe-Fee de Geus-Oei was already a professor at LUMC and the University of Twente. As Medical Delta professor, she has now also been appointed at Delft University of Technology. 'Talking with people from other disciplines always makes me immensely humble, because they look at…
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Huge advances could be made in the treatment of patients with childhood trauma
There’s a lot that goes wrong in the treatment of patients with PTSD caused by childhood trauma. Endowed professor Maartje Schoorl wants to resolve this by bringing scientific research closer to the practice. Inaugural lecture on Friday 29 April.
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uses artificial intelligence to calculate lung damage in coronavirus patients
With the aid of artificial intelligence (AI), care professionals at the LUMC (Leiden University Medical Center) are able to calculate quickly and accurately whether a coronavirus patient has suffered serious lung damage. They do this by putting a CT scan through the AI software of the CAD4COVID-CT p…
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Teaming up with Portugal: as a doctor, how do you talk to a patient?
As a doctor, coming to a decision together with a patient: how do you do that in the best possible way? Researchers Geert Warnar and Roosmaryn Pilgram, who jointly teach a course within the MA in Dutch Studies, are entering into a virtual collaboration with the Universidade NOVA de Lisboa to find the…
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‘Technological developments should be applied to patient care at a much faster rate’
An MRI scanner is much more than a machine alone. It is an extremely versatile technique that provides numerous opportunities for finding out more about the workings of the human brain, says Thijs van Osch, Professor of Radiology, with a particular emphasis on experimental cerebrovascular imaging. Inaugural…
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Court case of 15-year-old anorexia patient: force-feed or right to self-determination?
Via expedited proceedings at Leeuwarden Court of Appeal, a mother is trying to impose a relatively new treatment for her 15-year-old daughter’s eating disorder. The girl is suffering from anorexia nervosa and if she does not receive urgent treatment which the girl herself supports, there is a chance…
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Patient to plastic surgeon: ‘I want to look like my selfie.’
An image has great powers of persuasion. It is said that ‘a picture is worth more than a thousand words’. But these days, images can easily be manipulated with severe consequences. ‘Perhaps it’s time to reconsider the value we attach to images’, says Elize de Mul, whose PhD thesis deals with ‘digital…
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Two times KNMP Student Award for Leiden students
This year, two Leiden master students will be awarded a KNMP Student Award. Both Wisse van Os and Jip Linthorst will receive 1,000 euros from the Royal Dutch Pharmacists Association (KNMP) as a reward for their excellent study results, motivation and commitment.
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often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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4D Picture project
Helping cancer patients with treatment choices.
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Catherijne Knibbe
Science
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Treating Meningioma: does the patient benefit?
PhD defence
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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Predicting Outcomes in Patients with Kidney Disease
PhD defence
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Patient-relevant outcomes after kidney transplantation
PhD defence
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Measuring symptoms and functioning in glioma patients
PhD defence
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Traffic accident victims and polytrauma patients
PhD defence
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Bleeding in hemato-oncology patients
PhD defence
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Red cell transfusion in critically ill patients
PhD defence
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Inflammatory Bowel Disease in Older Patients
PhD defence
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Research
Knowledge on how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically-ill patients, is not only crucial for novel compounds, but also for existing drugs which are often used in an off-label manner in these special patient…
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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Stromal cells suppress immune response symptoms
A new therapy for the serious Graft-versus-Host disease
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Personalized Medicine
Assessing and implementing new diagnostics strategies for stratifying patients
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Determinants of and Interventions in Chronic Fatigue.
What are the most important perpetuating factors of chronic fatigue and chronic fatigue syndrome, and which interventions are effective in influencing these factors?
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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Neurofibromatosis Type I
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Cell Therapy
Decision support tool for cell therapy commercialization and business development
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Topic: Self-management in chronic diseases
Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Repair a bad kidney or make a new one to order
Searching for ways to delay the need for a transplant and trying to build kidneys to order.
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Ageing
As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Innovation in treatment and care
Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…
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Spontaneous hospitalization in the immediate aftermath of the Manchester arena bombing
This article presents an evidence-based investigation of spontaneous hospitalization and distribution of patients after the Manchester terrorist attack.