Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Hybrid Intelligence (HI) is the combination of human and machine intelligence, expanding human intellect instead of replacing it. HI takes human expertise and intentionality into account when making meaningful decisions and perform appropriate actions, together with ethical, legal and societal values.…

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Does a moving hybrid zone leave a genomic footprint?

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

What are the main issues leading to polarisation and division? What is the role of social exclusion in these processes? How can we inform and design better policies to safeguard young people from falling prey to intolerance and polarisation? The DRIVE project, led by Leiden University in The Hague,…

A comparative analysis of legitimation strategies in tree hybrid regimes: Russia, Venezuela, and Seychelles.

There are about 35,000 students with chronic illnesses in the Netherlands. If they cannot receive education in the classroom, they may be able to do so from home or a hospital with hybrid education. The question in this study is: how can interaction with the teacher and fellow students be promoted?

This project involves research into the oeuvre of the Sundanese sculptor Iko, who has worked for the Catholic mission in Java and has carved sculptures for a chapel and church in Ganjuran. The images were designed by the Catholic layman Jos Schmutzer and are characterized by a fusion in style and symbolism…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Intelligent machines are going to make ethical decisions too. Should a self-driving car be allowed to slam into pedestrians to save its passengers from a head-on collision? Should a negotiation app be able to detect stress in your opponent’s voice? And who makes these decisions: the user, the system’s…

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Promotor: H.J.M. de Groot

Prostate cancer (PCa) is one of the most prevalent cancer in males.

How do humans control their thoughts and actions, and what can high-field brain scanning reveal about the underlying processes?

Our annual "Science to Experience" exhibition of student works is hosted by the V2_ Lab for the Unstable Media. This year's theme is "HYBRID".

Ben Wielstra studies hybrid zones, regions in which distinct populations of organisms meet, mate and produce genetically admixed offspring. In the journal Current Biology, he introduces hybrid zones in an accessible way.

Leiden Physicists have found evidence for the Berry-force that could be used for driving tiny nanomotors, just like a river drives a water wheel. Nanomotors could be used for drug delivery in the human body. Publication in Beilstein Journal of Nanotechnology.

Raffaele Marchetti (2021). Hybrid Diplomacy with NGOs: The Italian Formula. Cham: Palgrave Macmillan. ISBN 978-3-030-86869-7, 135 pp., €46.00 (eBook).

From 16 to 19 September 2021 a hybrid conference will take place on animation in the Middle Ages. This conference is a cooperation between the University of Bergen (Norway) and the A. Zelwerowicz National Academy of Dramatic Art in Warsaw, Branch Campus in Bialystok (Poland).

In the present-day United States, to what degree(s) are far-right men and women similar and/or dissimilar in their motivating factors for engaging in far-right social movement activism?

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Intermediality, Media Practices and Media Literacy is one of the six research themes of the LUCAS Modern and Contemporary cluster.

While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.

Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

Each year, poppies disperse seeds that grow into a new generation of flowers. Sometimes, some of the seeds postpone their germination for a few years, for example when they’re covered by a layer of sand. Only when the sand disappears, do they start to sprout. Margriet Oomen did mathematical research…

A new study from Leiden researchers shows that the carbon emissions of building materials are set to grow if we do not act rapidly. Even with known interventions implemented in concert, these emissions are much larger than the remaining 1.5 degree budget for building materials at today’s share, the…

Promotor: Prof.dr. J. Memelink

How does invasive hybridization affect threatened native species?

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Blended and hybrid teaching are presented as crucial in promoting teaching innovation, as well as more flexible study approaches allowing students to develop their own tailor-made study programmes. While the strategy document focuses on the positive aspects of digital teaching tools, no systematic study…

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Book Presentation | Studium Generale Lecture

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Anthropology of Law in Muslim Sudan analyses the hybridity of law systems and the plurality of legal practices in rural and urban contexts of contemporary Sudan, shedding light on the complex relation between Islam and society.