1,845 search results for “development disease” in the Public website
-
IBL Spotlights
During the IBL Spotlights, researchers of our department discuss their newest findings and achievements. After the lectures, you are all invited to the reception on the first floor of the Sylvius building.
-
Discovery and characterization of new glucosylated metabolites: pathophysiological consequences
Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.
-
Willem Fibbe
Faculteit Geneeskunde
-
Bacteria inside plant roots battle fungal disease
Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…
-
Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
-
Leukemia treatment & cognitive development
-
-
NWO grant for super fast analysis of disease progression
New funding allows IBL-researcher Herman Spaink to purchase a measurement device for more studies on human diseases such as cancer and tuberculosis using zebrafish as the model system.
-
T-DNA integration and DNA repair of DSBs in plants
Identification and characterization of components of DNA repair pathways and their role in Agrobacterium T-DNA integration and repair of CRISPR/Cas induced DSBs.
-
Microbial Induction of Plant Resilience to Drought Stress (MicroRes)
What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?
-
ADAPTED
The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…
-
Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
-
Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
-
Pesticides and health – challenges and opportunities for exposure assessment
The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…
-
Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
-
Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
-
Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
-
Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
-
Deciphering the link between Iron and Brain Disease
Aceruloplasminemia is a very rare, genetic disease accompagnied with iron accumulation that causes movement disorder and brain damage at early age.
-
Elizabeth (Liesbeth) de Lange
Science
-
Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
-
Kiki Zanolie
Faculteit der Sociale Wetenschappen
-
Anna van Duijvenvoorde
Faculteit der Sociale Wetenschappen
-
Arnout Koornneef
Faculteit der Sociale Wetenschappen
-
Collaborating on big data to unravel disease processes
Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. This represents a new step towards ultimately being able to offer every patient more personalised treatment.
-
Inaugural lecture: Research into accelerating rare disease research through registries
On 3 April, Professor Syed Faisal Ahmed from the Leiden University Medical Center (LUMC) will give his inaugural lecture ‘Strength in Numbers’. He will emphasise the benefit of registries to rare disease research.
-
Immunity, Infection and Tolerance
The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.
-
Media use and brain development during adolescence
Nowadays children grow up with social media. This may influence the development of brain regions involved in social interaction. In their review article in Nature Communications, Crone and Konijn illustrate how neuroscience can contribute to a better understanding of how media and peers influence adolescents'…
-
AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
-
Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
-
Peer feedback in teacher professional development
This dissertation set out to provide both an integrated framework for the practices of teacher peer feedback and an in-depth understanding of teacher peer feedback in the Chinese vocational education context.
-
Andrea Spruijt
Faculteit der Sociale Wetenschappen
-
David Zetland
Faculty Governance and Global Affairs
-
Inge van der Weijden
Faculteit der Sociale Wetenschappen
-
Kiki Spaninks
Science
-
Evelien Urbanus
Faculteit der Sociale Wetenschappen
-
Christine Mummery
Faculteit Geneeskunde
-
Sheila van Berkel
Faculteit der Sociale Wetenschappen
-
Anar Ahmadov
Faculty Governance and Global Affairs
-
Barbara Gravendeel
Science
-
Jimena Pacheco Miranda
Faculteit der Sociale Wetenschappen
-
George Miley
Science
-
Marja Oudega
Faculteit der Sociale Wetenschappen
-
Jennifer Anderson
Science
-
Liza van den Bosch
Faculteit der Sociale Wetenschappen
-
Ili Ma
Faculteit der Sociale Wetenschappen
-
Nienke Wieringa
ICLON
-
Marieke Bos
Faculteit der Sociale Wetenschappen
-
Tales Yamamoto
Science
-
Zijian Li
Faculteit der Sociale Wetenschappen
-
Shannon Yuen
Faculteit der Sociale Wetenschappen