Electron microscopy has become an extremely important techniquein a wide variety of elds.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

From The Cognitive Continuum of Electronic Music:

How do we experience electronic music? How does electronic music operate on perceptual, cognitive and affective levels? What are the common concepts activated in the listener’s mind when listening to electronic music? Why and how are these concepts activated?

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

What is the Electronics Department?

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

This thesis describes a study from both a theoreticaL and an experimental point of view.

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

The aim of this facility is to accelerate biomedical research by providing access to advanced light and electron microscopy and by sharing expertise about sample preparation, imaging modalities, data storage and image analysis.

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

The principal aim of this research is to explore the confrontation between voice and electronics. These are often seen as being radically different from one another and many characteristics seem to be in opposition between them. However, they also have characteristics in common and they can influence…

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Science, Leiden Institute of Chemistry (LIC)

Promotor: Prof.dr. C.W.J. Beenakker

The dissertation describes TEM experiments on heterogeneous catalysts.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

What is the effect of practicing with electronic books on reading skills for grade 1 students?

My research focusses on site-specific compositional and performance practices of music for organ and electronics and their musical-spatial values.

Promotores: G.W. Canters, T.J. Aartsma

Beenakker

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Physicist Daniël Geelen has developed a new microscope that uses low-energy electrons. Those are less harmful to biological and organic materials. Geelen defends his PhD thesis on May 31st.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…

For the first time, physicists have visualized the ‘melting’ of electrons inside a special class of insulators. It allows electrons to move freely and turns the insulator into a metal and possibly later into a superconductor. Publication in Nature Physics.

The use of a new type of detector has generated a strong improvement in the resolution of electron microscopes. The 'low-energy electron microscope' (LEEM) can now be used for research on the thinnest possible materials. The tests with the detector represent the first result of the ESCHER project.

The Netherlands Organisation for Scientific Research (NWO) has made a subsidy of 17 million euros available to further develop a Netherlands network for electron microscopy (NEMI). The network comprises five UMCs and eight universities, with Utrecht in the coordinating role. From Leiden, the Institute…

PNAS publication on protein encounter complexes

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.

Lecture

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Bacteria are everywhere. They are the most abundant organisms on earth and impact all aspects of our lives. They determine our health and shape our environment. Ariane Briegel, professor of Ultrastructural Biology, freezes bacteria super fast to gain a true-to-nature image of the internal and external…

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

This dissertation derives from the development of tools for algorithmic composition which extract pitch materials from sound signals, analyzing them according to their timbral and harmonic properties, putting them into motion through diverse rhythmic and textural procedures.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…