2,073 search results for “binding study advice bsa” in the Public website
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Kabinetsvoorstel voor lager bindend studieadvies: geen goed plan
De Universiteit Leiden vindt de aanpassing van het bindend studieadvies geen verstandig plan.
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Prediction of binding kinetics
Supervisor: Gerard van Westen
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Drug-target binding kinetics in vivo
A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.
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The Role of Target Binding Kinetics in Drug Discovery
Source: ChemMedChem (2015)
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Physicochemical analysis of allosteric binding pockets
Supervisor: Gerard van Westen
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Sodium ion binding pocket mutations and adenosine A2A receptor function
Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Paula van den Berg
Science
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Leiden University modifies BSA regulation for the first year and ends experiment with second year
Leiden University is ending the experiment with the Binding Study Advice in the second year of the bachelor's programme (BSA 2) with immediate effect. Under the terms of BSA 2, students were required to obtain 90 credits within two years, including their first-year diploma.
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Personal advice
If you still have questions and would you like to talk to someone about them, Leiden University offers the following options.
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Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
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Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands
Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.
- Student Guide
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Insights into microtubule catastrophes: the effect of end-binding proteins and force
For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.
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Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
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The Social Ties that Bind: Unraveling the Role of Trust in International Intelligence Cooperation
Together with Pepijn Tuinier and Thijs Brocades Zaalberg, Sebastiaan Rietjens researched the role of trust in an international intelligence cooperation.
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Rosema & Louwerse, ‘Response scales in Voting Advice Applications’
Voting Advice Applications represent popular election campaign tools in many countries, enabling voters to discover which party or candidate provides the best match with their political preferences. Political scientists Martin Rosema (University of Twente) and Tom Louwerse (Leiden University) examine…
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BSc Security Studies
On this page you will find all information about the Bachelor of Security Studies that you need as a first-year student.
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Quantifying nucleosome dynamicsand protein binding with PIE-FCCS and spFRET
In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…
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1 (hERG)-induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv 11.1 (hERG) inhibitors
Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)
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Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary
The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…
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English Usage Guides: History, Advice, Attitudes
The second major collection of papers from the Bridging the Unbridgeable project.
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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)
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Bachelor Q&A (English)
On this page you can find answers to frequently asked questions.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Christopher Green
Faculty of Humanities
- Frequently Asked Questions
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Channa Li
Faculty of Humanities
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About the programme
The 3 years bachelor's specialisation Heritage and Society offers a versatile programme in which you explore the cultural heritage of past and current societies. With your obtained knowledge you will learn to better understand cultures from the past. Moreover, with your insights in societal issues in…
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Come and visit us!
As a university, we offer you the best education you can get. Professors, tutors and lecturers are ready to teach and guide you. But we do more than that. Of course, studying is your own responsibility, but we are happy to help if you need support. You decide what and when; online or on campus. These…
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Hodegetics: Language of Vice in Student Advice Literature, 1700-1900
This project analyzes to what extent hodegetical textbooks relied on each other in warning their readers against vicious habits, how much continuity their catalogs of vice displayed, and to what extent vices that persisted throughout the 18th and 19th centuries were associated with easy-to-remember…
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Xiao Luo
Faculty of Humanities
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Philomeen Dol
Faculty of Humanities
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Shirley Alexander
Faculty of Humanities
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Amirardalan Emami
Faculty of Humanities
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Yujing Tan
Faculty of Humanities
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Nico Kaptein
Faculty of Humanities
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Steven Hagers
Faculty of Humanities
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Haneen Omari
Faculty of Humanities
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Xiong Xiong
Faculty of Humanities
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Boudewijn Walraven
Faculty of Humanities
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Geoffrey Cain
Faculty of Humanities
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Jurre Knoest
Faculty of Humanities
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Aihua Li
Faculty of Humanities
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Peter Verhagen
Faculty of Humanities