How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?

For a first time the atlas maps the soil biodiversity of the entire planet, and provide s comprehensive analysis of human-induced threats to soil organisms and soil functioning, facilitating development of new policies to protect soil and soil organisms.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Promotores: J. Jonkers, K.E. de Visser

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.

Eine Archäobotanische untersuchung zu Umwelt und Landwirtschaft der Ältesten Bankkeramik.

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

I. Die Ausgrabungen am Weinberg 1965 bis 1970. Mit Beiträgen von A.T. Clason, M.E.Th. de Grooth, L.H. Keeley und K.J.H. Vriezen.

How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

This dissertation provides a detailed description of the interaction between verb semantics and the two grammatical voice categories in the Vedic Sanskrit of the Rigveda.

Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

We examine how soil-derived legacy effects of plants structure natural ecosystems, determine aboveground plant insect interactions, and how we can use soil legacy effects to restore degraded ecosystems.

Analecta Praehistorica Leidensia is the annual journal of the Faculty of Archaeology (formerly the Institute of Prehistory), Leiden University.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

Archaeobotanic research by prof. dr. C. Bakels and students on agriculture.

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?

We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

How do mycobacteria subvert the defenses of host immune cells?

This doctoral thesis focuses on Paisiello's partimenti and how to approach their realization and performance.

This dissertation deals with Hegel’s theory of the sublime (das Erhabene). I focus specifically on die heilige Poesie (sacred poetry), a form of art that he identifies with the Judaic Psalms and which I claim to be the core of Hegel’s approach to sublimity. I claim that Hegel’s apparent lack of interest…

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

How did a circle of Soviet artists and writers virtually unknown until perestroika turn into Russia’s most influential contemporary art movement? This book reconstructs the cultural history and canonization of a group of painters and poets known as the Moscow conceptualists, who paradoxically did not…

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

My research addresses the function of the much-debated particle -nā in Biblical Hebrew, often translated with “please”, from the point of view of the most important ancient Bible translations (Greek, Syriac, Latin). It combines textual criticism, translation technique, discourse pragmatics, and the…

Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.

Music from a compostable cello, photographs and scents of fungi and a woven tapestry. With her upcoming multimedia project Super Organism, visual artist Suzette Bousema enables people to experience the underground fungal network with all their senses. Environmental scientist Nadia Soudzilovskaia and…

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

The recent rise in global migration movements and the simultaneous attempts to prevent migrations to the Global North in general and Europe in particular have produced numerous images and narratives that try to record and convey these events and their actors.

Leaf-eating caterpillars greatly enrich their intestinal flora by eating soil. Even effects of plants that previously grew in that soil can be found back in bacteria and fungi in caterpillars. Researchers from the Netherlands Institute of Ecology (NIOO-KNAW) and Leiden University write about this discovery…

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

How can zebrafish research help to understand and fight human cancer?