181 search results for “anti-cancer drug steen” in the Staff website
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Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
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Lowlands as lab: virtual trips in the name of science
While tens of thousands of visitors dance to deafening music, a team of Leiden psychologists are trying to collect data for their research at Lowlands. How do festivalgoers experience a virtual trip? And what role do factors such as too little sleep and whether they have experience with psychedelics…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Combating antibiotic resistance together
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…
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'Working with PhD candidates gives me energy'
Erik Danen is the new Dean of the Graduate School from 1 January. He is a professor at the Leiden Academic Centre for Drug Research and conducts research into cancer drugs. Danen is really looking forward to it: ‘PhD candidates are a special group: that's what I like to dedicate myself to.’
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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Gilles van Wezel steps down as SD of the IBL: Hubertus Irth appointed as temporary replacement
Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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Spinoza Prize for Professor Bernet Elzinga
How can parents avoid passing on stress and mental health problems to their children? Professor of Stress-Related Psychopathology Bernet Elzinga develops simple interventions to help both parents and young people. For her research, she has been awarded the Spinoza Prize, the highest academic honour…
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Historic Literary Guided Tour - Literary Leiden
Stadswandeling
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Rubicon grant for four Leiden researchers
Four promising young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This grant will enable them to gain valuable research experience at top universities abroad.
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A plan of the faculty: 'In France, it would have been a plan of the boss'
The moment has finally arrived: after months of hard work, the strategic plan is finished. It was an interesting period, thinks core group member Sylvestre Bonnet. 'How we finally arrived at this strategic plan was very different from what I had thought beforehand.'
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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The hunt for nanoplastics is on
How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.
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Exhibition shows the ‘beauty and power’ of mathematics
In the ‘Imaginary’ exhibition, its curators show how society is made up of mathematics. From algorithms that save lives to ones that generate art. The exhibition is from 2 June to 25 July at Oude UB in Leiden.
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Be amazed and inspired during the Leiden Science Family Day!
On Sunday 8 October 2023, during the Weekend van de Wetenschap, the Faculty of Science of Leiden University will open its doors to anyone curious about science from 11.00 to 16.00 hrs! Explore a world of wonder and discovery; where science is transformed into an unforgettable adventure. Intriguing…
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Heineken Young Scientists Award for three Leiden researchers
Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.
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Master's student Nicole ter Laak wins KNMP Studentenprijs 2023
Biopharmaceutical sciences master's student Nicole ter Laak has won the KNMP Studentenprijs 2023. She wins the prize for her research project on dosing guidelines of antibiotics in newborn babies with a very low birth weight for gestational age.
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Artificial microswimmers work together like bacteria
Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Kiem initiative culminates in plan to apply for larger grant
The interdisciplinary Kiem project ‘Violence as a Population Health Problem’ has resulted in a plan to apply for a large, yet-to-be-decided research grant. The so-called pressure cooker session at the heart of the project proved very effective.
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Visit by Members of Parliament highlights interdisciplinary research and collaboration
High-quality education, research involving multiple faculties, collaboration between universities and central government funding to make all this possible: these were the topics covered in a working visit of the Standing Committee for Education, Culture and Science (OCW) to the Association of Universities…
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IBL Spotlights - Development & Disease
Lecture
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Ecologist Michiel Veldhuis is the Discoverer of the Year 2020
Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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Executive Board column: Annetje Ottow on the importance of student associations
Now the introduction weeks can go ahead as usual, the new students’ enthusiasm is overwhelming. It’s back to normal for the student associations too, having had a hard time of it during the pandemic.
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‘Sleep should play a greater role in lifestyle research’
Sleep disorders have a significant influence on our physical and emotional health. Sleep should therefore receive more attention within lifestyle medicine, says Professor Gert Jan Lammers. He will give his inaugural lecture on Friday 20 May entitled: ‘Getting to sleep’.
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ERC Advanced Grants for four Leiden researchers
From a new generation of antibiotics and more-effective vaccines to a map of dark matter and new light on Hindu traditions. Four researchers from Leiden University have received a prestigious €2.5m ERC Advanced Grant to develop their research.
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Lindsey Burggraaff wins Krijn Rietveld Memorial Innovation Award
Data scientist Lindsey Burggraaff has won the second edition of the Krijn Rietveld Memorial Innovation Award. She receives the prize for her research into bioactive substances in food. ‘Burggraaff's work is situated at a unique intersection of data science, biochemistry and the fields of food and nutrition,’…
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De dag van Jasper
Jasper Knoester is de decaan van de Faculteit Wiskunde & Natuurwetenschappen. Hoe gaat het met hem, wat doet hij precies en hoe ziet zijn dag eruit? In elke nieuwsbrief geeft Jasper een inkijkje in zijn leven.
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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GTGC lunch seminar series: an international, interdisciplinary scope
Starting February 6, the Leiden interdisciplinary research programme Global Transformations and Governance Challenges (GTGC) will host a lunch seminar series on pressing global governance issues. The series will feature researchers from various disciplines. It promises to be a trove of inspiration and…
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Three awarded research projects in NWO-XS call
Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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How do we get the we-feeling on the faculty? This is how Joost Batenburg thinks
As professor of computer science at LIACS and programme director of incentive programme SAILS, Joost Batenburg knows better than anyone what is going on in the faculty. Over the past three years, he learned at lightning speed what is going well and where sensitivities lie. 'We need to move more towards…
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300 million euros for new international stem cell consortium
The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…
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Biology student Martijn Verkuilen wins Unilever Research Prize
Martijn Verkuilen is the winner of the Unilever Research Prize 2022. By transferring DNA from a plant into yeast, he made the first move to produce a new drug for type 2 diabetes. He collected his prize in Wageningen on 24 November.
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PhD Graduate Van Groesen: ‘Nothing is too crazy to try.’
In a world where bacteria are increasingly resistant to antibiotics, Emma van Groesen set out to find a solution. This month she obtained her PhD, after four years of research into new variants of the antibiotic vancomycin. With success.
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
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Innovating Cell Pharmacy with stem cells
Lecture
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Improving Nature’s Antibiotics to Overcome Resistant Bacteria
Lecture, NGL-lezing
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Interdisciplinary collaboration in Leiden: discover the interdisciplinary research programmes
Event for all Leiden researchers
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CCLS Seminar
Lecture, Center of Computational Life Sciences
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.