NVIC would like to invite you to Tilly Mulder's second exhibition. This time around a new series of paintings, names 'Mindscapes', will be on show.

How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?

How do insurance products transform intimate and personal relations? What are the consequences of the classifications that insurance companies use and how do these affect solidarity, morality and inequality?

Young people are more likely to find long texts unappealing to read, particularly with all the digital distractions. To improve young people’s reading skills, Elise Swart and Hannah De Mulder are starting an innovative study to make reading fun again.

Research question

Key publications of the Cardiovascular Pharmacology group

Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Part of ‘Moralising Misfortune: A comparative anthropology of commercial insurance’, an ERC Consolidator project of Erik Bähre.

Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)

The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.

Grants awarded to molecular physiology research

Why do plants produces always produced so many slightly differing metabolites within a particular chemical class?

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

Read all papers and other types of publication created by the project.

BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…

Experimental research

A full overview of MCBIM PhD theses.

Which plants are depicted, described or collected in these century-old objects? Who made these objects, where and for what purpose? What is their scientific and societal relevance today?

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

The recognition that there may be more, so-called allosteric binding sites on a given receptor has also fueled our synthetic efforts. Over the last few years we have focused on many drug targets (adenosine A1, A2A and A3 receptors, the mGlu2 receptor and a classic ‘anti-target’, the hERG channel) to…

The specialisation in European Union Studies offers students an opportunity to study the processes of European integration from a multi-disciplinary perspective and combines academic excellence with practical insights into the processes of policymaking in Europe.

In 2022, many of our staff and students won fantastic prizes and were awarded important research grants.

The Municipality of The Hague, Leiden University and CBRE Investment Management (CBRE IM) will together try to realise a University building in the former Hudson’s Bay premises at Grote Marktstraat 48-50/Spui 3. This will facilitate the growth of Campus The Hague. A cooperation agreement was signed…

The Dies Natalis for alumni on 11 February was an online event. Almost 1,000 alumni tuned in to Bastiaan Rijpkema’s interview with Annetje Ottow, who had then been President of Leiden University’s Executive Board for all of three days. Alumni are part of her portfolio on the Executive Board.

A group of Leiden Computer Science students, with Simone Cammel, Bas Mulders, Sufeng Li, Edward Magron en Kostas Tsogkas, won the prestigious business game 'StrICTly For Business'.

The Klokhuis dedicates a special episode to Leiden alumnus and famous scientist Christiaan Huygens. Part of the episode was recorded at the Leiden Observatory. Leiden researchers also helped shape the episode, which debuts on Tuesday 2 November.

Deze zomer verscheen een prachtig boek: "Geleefd geloof. Het geloofsleven van boeren en burgers in Friesland en de Ommelanden van Groningen,1250-1580". Bijdragen zijn er van beide redacteuren, Anneke B. Mulder-Bakker en Rolf H. Bremmer Jr, en van o.a. Sible de Blaauw, Jos Koldeweij, Catrien Santingh,…

Onlangs verscheen het boek ‘Afgrond zonder vangnet’ van Yra van Dijk, hoogleraar Moderne Nederlandse Literatuur. In haar boek analyseert ze verschillende thema's in het werk van Arnon Grunberg.

What is the Fine Mechanical Department?

The CADS Research Cluster People, Power and Diversity aims to further theoretical and methodological debates on the classifications of human difference, such as gender, race, ethnicity, sexuality, class, age, ability, religion, level of development, time, etc., and the way these classifications organize…

The Leiden University Centre for Linguistics (LUCL) aims to demonstrate its relevance to society by means of high-quality research, excellent education and various outreach activities. A few highlights: