Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in

How do macrophages and neutrophils contribute to metastatic onset?

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

PhD defence

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in

PhD defence

PhD defence

The interdisciplinary network Faith in Democracy (FID) studies the religious, sometimes even totalitarian, assumptions behind the concept of

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

The Telders Moot Court is an important part of the legal education of a next generation of international lawyers.

In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

The Leiden Ancient History specialization concentrates on the study of the economies, societies and cultures of the large empires of the Graeco-Roman world, starting with the empires of Alexander the Great and his successors.

This book explores the spiritual potential of faith, mysticism and transcendence in answer to the dangers of a mythologised state and the sacro-sanctification of (liberal) democracy and its rule of law.

Modern receptions of Graeco-Roman Antiquity are important ideological markers of the ways we envisage our own twenty-first-century societies. An urgent topic of study is: what kinds of narratives – sometimes controversial – about Antiquity do people create for themselves at this moment in time, and…

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.

The center studies the many ways in which issues of law and justice are dealt with in art and literature with a focus on liminal issues and cases. These are issues and cases where law comes to the limits of what it is capable of dealing with and art and literature explore the implications of what is…

Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

In less than two years’ time, Florian Volz and Timo Schmidt, both German students studying International Studies in The Hague, went from knowing each other only vaguely to sharing a small tent and a bank account. Sounds like any other ordinary relationship, right? Well, not exactly. These two honours…

Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.

How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?

How did colonial law work to turn people into property? This project argues that colonial ideas about households and domestic authority were critical to legal processes of enslavement in the early modern Dutch empire. Using colonial court records from Dutch Brazil, Suriname, and the Moluccas, the project…

On 10 January, Ben Van Rompuy spoke at the New Year's meeting of the Dutch Competition Law Association in Amsterdam.

Timo Schmidt and Florian Volz, both International Studies students, have travelled the route many refugees took to reach Europe by bike in the summer of 2016. Through crowdfunding, they want to finance their documentary about this journey. With three days to go, they are at 90% of their target amount…

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Is the legitimacy of law and governance of multilevel jurisdictions diminishing? What is the significance of (diminishing) legitimacy for the effectiveness of law? These kinds of questions about the legitimacy of the supranational formation of law, its application, and the policy and governance based…

In the Criminal Justice research programme, legal experts, criminal law experts and social scientists – many of whom are criminologists – collaborate on various projects. The research programme focuses on the content and form of decisions that are, can and may be taken in the criminal justice chain…

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

The Oncode Institute is a new international network organisation that focuses on making sure that new scientific findings on cancer are implemented in patients as rapidly as possible. Two young female researchers at Leiden University have been selected to join Oncode: Laura Heiman (Leiden Academic…

Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

PhD defence