574 search results for “covid-19 vaccine” in the Public website
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Formulation of Peptide-Based Cancer Vaccines
PhD defence
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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Therapeutic Immunomodulation
The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.
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Immunity, Infection and Tolerance
Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…
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Conflict resolution by internet platforms
The Covid-19 'infodemic' and conflict resolution by internet platforms.
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Innovation in treatment and care
Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…
- Health Diplomacy
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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Gaining control of lipid-based nanomedicine by understanding the nano-bio interface
Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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A Harmonised EAC COVID Pass to Re-Kindle Intra-Regional Trade
COVID-19 poses a significant barrier to intra-regional trade within the EAC, causing interminable hold-ups at the internal borders.
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Anne Meuwese and Bart Custers in Trouw on Covid apps
The more people are vaccinated, the more society can slowly reopen. Technological developments, like the Covid passport and other apps, can play a role in this. Artificial Intelligence could help greatly in developing the vaccine passport and the Covid-19 exposure notification app, Anne Meuwese and…
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Biologics Formulation
A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…
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Antibody Glycomics Signatures of SARS-CoV-2 Infection and Vaccination
PhD defence
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Learning the Right Lessons for the Next Pandemic
This report highlights the huge potential of public inquiries to ensure that lessons are learned from COVID-19 to help the UK prepare for a future pandemic.
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Targeting of antigen-presenting cells with mannosylated conjugates
This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.
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Vaccination: intradermal administration, duration of protection, and compromised immunit
PhD defence
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Monitoring the immune responses to vaccination and infection
PhD defence
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Research lines
Current research at the Skin Barrier and Vaccination group.
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COMET. Human Subject Research and Medical Ethics in Colonial Southeast Asia
Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.
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Voices of Young Academics
We as Young Academy Leiden are continuously educating ourselves and are listening to the voices coming from our own university, especially the young academics.
- Fake News/Disinformation
- Populism
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Formulation of biopharmaceuticals
Formulation of biopharmaceuticals
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Immunity, Infection and Tolerance
The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.
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Immunotherapy to limit atherosclerosis-projects
For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.
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Fall of Misinformation Series: Suzan Verberne
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Fall of Misinformation Series: Ionica Smeets
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Zwitterionic oligosaccharides: charging the immune system
How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?
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Block 4
In the overview below you can find the LUC Newsletters that were send out during block 4 in semester 2 of academic year 2019 - 2020.
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LEGITIMULT - Legitimate Crisis Management and Multi-level Governance
LEGITIMULT examines how Covid-19 measures by governments impact multilevel governance and democratic governance in 31 European countries
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The Future of Multilateralism: Global Cooperation and International Organizations
The Future of Multilateralism addresses current challenges and future perspectives of international and regional organizations. It aims to uncover how stable the foundations of global cooperation really are, particularly in the light of the latest unilateral and protectionist practices of international…
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Bolivia at the Crossroads: Politics, Economy, and Environment in a Time of Crisis
As Bolivia reels from the collapse of the government in November 2019, a wave of social protests, and now the impact of Covid-19, this book asks: where next for Bolivia?
- Blog Posts Archive
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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REACT Study
The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…
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Venue
Due to the Covid-19 pandemic SIP 2021 will be held online.
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Towards an Interspecies Health Policy: Great Apes and the Right to Health
Many dangerous diseases such as COVID-19, Ebola and Q fever have jumped from animals to humans. But it is not only because of these diseases that we should include animals in our health policy, but also because of their right to health.
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National identity predicts public health support during a global pandemic
Honorata Mazepus and Jaroslaw Kantorowicz are assistant professors at the Institute of Security and Global Affairs. Mazepus and Kantorowicz are one of the authors of this article in Nature on the role of national identity on public health support during global pandemics.
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Public Health and the American State
This book explores how public health concerns and political agendas influenced each other in the US over the past century.
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Editorial: Sanity and Resilience in Times of Corona
This editorial to RHCPP discusses how COVID-19 can be seen as a 'creeping crisis' according to the authors of its lead article (Boin et al, 2020) and how resilience may depend on the real heroes behind the scenes of response to disaster and adversity.
- Digital Diplomacy (incl. TechPlomacy and Mediatisation)
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Advances in clinical development for vaccines and therapeutics against respiratory virus infections
PhD defence
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chemistry approach for potentiating live attenuated whole-organism vaccines
PhD defence
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Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…