The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.

The SPS Monitor measures your sensory stimulus sensitivity. Sensory stimulus sensitivity refers to one's sensitivity to subtle environmental stimuli, the depth and intensity with which these stimuli are processed and the impact this has on one's functioning.

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A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…

The transition period in which men become fathers might provide an important window of opportunity for parenting interventions that may produce long-term positive effects on paternal care and, consequently, child development. Existing prenatal programs traditionally focus on maternal and infant health…

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

A study on the development of prosocial behaviour.

PhD candidates from Institutions for Conflict Resolution (COI), Eva Grosfeld (Leiden University), Marlou Overheul (Utrecht University), and Amarins Jansma (social psychology, Utrecht University), won the KLI seed money grant for research on the influence of politically sensitive cases on public trust…

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

This thesis discusses the discovery potential of Intensity Frontier experiments.

Promotor: E. Bouwman Co-Promotor: S. Bonnet

Lecture, Com(parative) Syn(tax) Series

Promotor: T. H. Oosterkamp

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

John van Noort

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Making sensitive data reusable through synthetic data generation

Mapping the neural mechanisms underlying social motivations of adolescents and adults

Social aspects of the learning environment, also called classroom climate, are important for students’ cognitive and affective learning outcomes. In this thesis the classroom climate is operationalised by means of two components: the teacher-class relationship and classroom discipline.

The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.

A lot of our research is performed at temperatures close to absolute zero, among other reasons because this increases the sensitivity of the measurements. 

One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…

Our core themes, which our programmes are about, are: Public Affairs, Leadership, Political-Administrative Sensitivity, Safety and major social issues.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

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In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

What is the neural basis of social decision-making across childhood, adolescence and adulthood and what are the developmental patterns in terms of behavior and brain activation?

Complaints against decisions not to prosecute in socially sensitive issues.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

It is in the interest of all democracies for young people to learn the value of free debate, even on sensitive and potentially divisive issues like terrorism, argue Thorbjørn Jagland (secretary general of the Council of Europe), Sayeeda Warsi (UK parliamentarian), and Francesco Ragazzi (Institute of…

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotor: E. Bouwman, Co-promotor: S. Bonnet